Version2.0
2020-02-27T20:40:13Z
10.1021/jm300687e
Gaussian16
RevisionB.01
PWARBURT
03-Feb-2020
#N HF/6-31G(d) OPT=(MaxStep=1) FREQ IOp(6/10=2,6/11=2,6/12=2)
DUDE Oc6ccc(c2sc1cc(O)ccc1c2C(=O)c5ccc(N4CCN(C3CCCC3)CC4)cc5)cc6 301603 CHEMBL366928
RHF
6-31G(d)
(6D,7F)
Oc6ccc(c2sc1cc(O)ccc1c2C(=O)c5ccc(N4CCN(C3CCCC3)CC4)cc5)cc6
C01[X(C30H30N2O3S1)]
192
C1
604
Oc1ccc2c(c1)sc(c2C(=O)c1ccc(cc1)N1CCN(CC1)C1CCCC1)c1ccc(cc1)O
Oc1ccc2c(c1)sc(c2C(=O)c1ccc(cc1)N1CCN(CC1)C1CCCC1)c1ccc(cc1)O
Oc1ccc(cc1)c2sc3cc(O)ccc3c2C(=O)c4ccc(cc4)N5CCN(CC5)C6CCCC6
InChIKey=XNGJGVJVIOZPEE-UHFFFAOYSA-N
InChI=1S/C30H30N2O3S/c33-24-11-7-21(8-12-24)30-28(26-14-13-25(34)19-27(26)36-30)29(35)20-5-9-23(10-6-20)32-17-15-31(16-18-32)22-3-1-2-4-22/h5-14,19,22,33-34H,1-4,15-18H2
InChI=1/C30H30N2O3S/c33-24-11-7-21(8-12-24)30-28(26-14-13-25(34)19-27(26)36-30)29(35)20-5-9-23(10-6-20)32-17-15-31(16-18-32)22-3-1-2-4-22/h5-14,19,22,33-34H,1-4,15-18H2
Oc6ccc(c2sc1cc(O)ccc1c2C(=O)c5ccc(N4CCN(C3CCCC3)CC4)cc5)cc6
C01[X(C30H30N2O3S1)]
192
C01
604
Oc1ccc2c(c1)sc(c2C(=O)c1ccc(cc1)N1CCN(CC1)C1CCCC1)c1ccc(cc1)O
Oc1ccc2c(c1)sc(c2C(=O)c1ccc(cc1)N1CCN(CC1)C1CCCC1)c1ccc(cc1)O
Oc1ccc(cc1)c2sc3cc(O)ccc3c2C(=O)c4ccc(cc4)N5CCN(CC5)C6CCCC6
InChIKey=XNGJGVJVIOZPEE-UHFFFAOYSA-N
InChI=1S/C30H30N2O3S/c33-24-11-7-21(8-12-24)30-28(26-14-13-25(34)19-27(26)36-30)29(35)20-5-9-23(10-6-20)32-17-15-31(16-18-32)22-3-1-2-4-22/h5-14,19,22,33-34H,1-4,15-18H2
InChI=1/C30H30N2O3S/c33-24-11-7-21(8-12-24)30-28(26-14-13-25(34)19-27(26)36-30)29(35)20-5-9-23(10-6-20)32-17-15-31(16-18-32)22-3-1-2-4-22/h5-14,19,22,33-34H,1-4,15-18H2
3763.9566929084
-1884.5035612
1-A
29227.9664
132
472
604
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9.89942
-4.6257 -0.7563 -2.4466
5.2872
|XX|YY|ZZ|XY|XZ|YZ|
-218.5346 -202.0215 -217.4288 -11.5587 -2.1567 -9.6263
|XX|YY|ZZ|XY|XZ|YZ|
-5.8729 10.6401 -4.7672 -11.5587 -2.1567 -9.6263
|XXX|YYY|ZZZ|XYY|XXY|XXZ|XZZ|YZZ|YYZ|XYZ|
-178.5729 -42.6260 -14.4512 72.6035 -117.6076 33.1469 -49.9112 39.0054 -41.2154 -33.4352
|XXXX|YYYY|ZZZZ|XXXY|XXXZ|YYYX|YYYZ|ZZZX|ZZZY|XXYY|XXZZ|YYZZ|XXYZ|YYXZ|ZZXY|
-31873.2643 -5364.7878 -2060.7380 -628.7815 207.2851 -770.2794 -395.9547 -99.3196 -2.3995 -5710.6595 -5773.2102 -1240.4518 -171.4851 156.2619 72.5792
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498.19771
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|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|
8.4658 17.3502 24.3532 31.8474 39.0161 44.0450 53.6012 60.0700 62.6995 71.5358 91.1625 107.1926 121.8155 128.5909 137.4179 147.9909 187.7214 206.5555 211.0280 218.7085 246.6056 252.8365 273.8485 284.2893 292.8007 297.9808 325.7799 327.8927 335.2209 368.2437 374.2184 406.9799 428.9018 438.9421 445.5159 454.8547 462.9713 464.0724 473.2480 486.1965 492.4661 511.6177 525.9725 530.2083 544.1362 573.0792 584.2809 595.2320 608.4673 644.3891 649.0814 658.4888 681.9040 696.5150 697.9266 722.1165 741.7411 767.6225 778.6594 799.1998 808.3349 827.4726 846.8668 847.2756 884.8033 888.0883 903.3550 914.0337 921.5579 925.8319 929.7125 939.0221 944.7493 951.3563 953.2727 966.9791 968.0288 971.2835 993.6121 1021.4959 1028.4220 1040.8771 1051.6548 1066.3324 1076.7804 1079.3734 1092.5820 1095.8795 1104.9765 1106.8335 1112.0244 1120.2210 1120.6818 1138.7577 1139.1670 1158.5255 1182.0435 1185.0606 1203.3674 1205.7433 1226.4183 1231.8873 1239.9097 1245.2050 1278.9154 1280.6719 1282.1304 1299.6042 1302.3610 1309.7913 1321.5217 1335.3545 1338.6558 1344.1449 1349.4506 1351.8071 1361.6591 1367.4916 1378.2891 1380.7922 1389.9198 1408.1184 1412.3344 1431.1907 1435.6968 1437.1127 1442.2615 1453.4810 1461.5485 1474.5869 1476.1520 1485.1807 1491.4224 1502.4508 1507.8565 1516.4973 1545.1508 1551.4932 1571.6456 1579.2978 1591.1042 1594.5514 1596.0156 1634.0960 1641.5701 1643.7472 1648.1547 1649.8160 1656.3047 1657.2350 1665.9788 1674.0721 1687.3849 1691.4641 1747.9664 1755.6608 1774.2124 1786.2276 1805.3584 1817.4482 1820.9372 1943.6697 3087.7602 3121.3647 3131.6069 3152.5117 3163.5945 3205.3244 3207.0180 3216.6191 3232.3539 3246.2568 3259.4192 3263.6983 3272.2429 3276.9435 3285.4716 3290.0681 3305.5063 3347.1625 3349.2597 3378.9072 3382.6209 3384.7681 3393.4232 3395.9095 3400.8964 3401.4890 3409.3252 3412.5445 4116.0360 4119.4664
6.6798 3.5098 4.1310 3.4971 3.3545 4.2322 5.1212 5.3243 5.7900 3.3405 3.9094 3.5727 4.7968 5.7959 4.7224 5.5291 4.7884 5.6409 3.3930 3.9947 4.4769 7.0359 2.9488 4.5487 2.2225 1.3924 3.9350 1.6348 2.1408 3.8119 5.9508 4.2388 4.0014 5.1536 2.5947 4.0293 3.0625 3.0659 6.2688 3.1178 3.6512 6.1808 4.2141 2.5967 2.7031 6.0438 4.9822 3.2663 3.1743 4.2734 2.8898 4.2316 5.1601 5.6080 6.3546 4.7452 2.9572 7.0504 3.9822 3.8680 4.3468 3.9621 2.2626 1.6830 2.1858 5.5610 3.5314 1.5894 1.5361 1.9712 2.9636 1.6817 2.6655 1.6523 1.6641 2.2093 1.5195 2.4123 6.2402 2.1516 2.9910 4.8583 2.1763 1.5918 1.4518 1.3415 1.3026 1.3862 2.8114 1.3763 2.4842 2.4261 1.4550 2.2787 2.8000 2.2509 2.6350 1.8099 1.8852 2.4588 1.6224 2.0001 2.0679 2.2071 2.3997 2.1016 2.6755 1.1949 1.8966 1.7792 1.6637 1.3672 2.1901 1.3637 1.7688 1.3516 1.7995 3.4114 1.7204 2.1633 3.1878 1.1246 3.5823 1.3262 2.2848 1.4111 1.2747 1.3058 1.4522 1.4183 1.5921 2.6807 1.3938 1.5658 1.5040 1.2921 1.4631 1.6106 1.4516 2.7404 2.7462 2.6302 1.6866 1.0796 1.0838 1.0966 1.1026 1.1045 2.6332 1.1850 1.1114 1.1117 2.6186 2.5964 6.4588 5.8643 7.4252 6.4328 5.2078 5.7588 5.6273 12.8919 1.0827 1.0749 1.0746 1.0715 1.0735 1.0734 1.0619 1.0632 1.0670 1.0993 1.0975 1.1037 1.0934 1.1057 1.0896 1.0894 1.0903 1.0905 1.0911 1.0946 1.0902 1.0897 1.0893 1.0933 1.0962 1.0943 1.0947 1.0944 1.0668 1.0668
0.0003 0.0006 0.0014 0.0021 0.0030 0.0048 0.0087 0.0113 0.0134 0.0101 0.0191 0.0242 0.0419 0.0565 0.0525 0.0713 0.0994 0.1418 0.0890 0.1126 0.1604 0.2650 0.1303 0.2166 0.1123 0.0728 0.2461 0.1036 0.1417 0.3046 0.4910 0.4137 0.4337 0.5850 0.3034 0.4912 0.3868 0.3890 0.8272 0.4342 0.5217 0.9532 0.6869 0.4301 0.4716 1.1695 1.0021 0.6818 0.6924 1.0455 0.7173 1.0811 1.4137 1.6030 1.8237 1.4579 0.9586 2.4477 1.4225 1.4556 1.6734 1.5984 0.9561 0.7119 1.0082 2.5841 1.6979 0.7824 0.7686 0.9955 1.5093 0.8737 1.4017 0.8811 0.8910 1.2171 0.8389 1.3408 3.6298 1.3228 1.8638 3.1012 1.4181 1.0664 0.9918 0.9208 0.9162 0.9808 2.0224 0.9934 1.8100 1.7937 1.0766 1.7410 2.1408 1.7800 2.1692 1.4976 1.6085 2.1061 1.4377 1.7883 1.8731 2.0163 2.3126 2.0308 2.5913 1.1891 1.8954 1.7984 1.7119 1.4364 2.3124 1.4517 1.8978 1.4552 1.9659 3.7587 1.9256 2.4300 3.6284 1.3138 4.2101 1.6004 2.7748 1.7171 1.5622 1.6254 1.8277 1.8170 2.0441 3.4838 1.8266 2.0825 2.0147 1.7508 2.0581 2.2842 2.1125 4.0272 4.0961 3.9402 2.5313 1.6984 1.7207 1.7457 1.7647 1.7713 4.2562 1.9175 1.8174 1.8357 4.3929 4.3767 11.6271 10.6499 13.7711 12.0927 10.0007 11.2075 10.9937 28.6954 6.0820 6.1701 6.2091 6.2744 6.3304 6.4974 6.4347 6.4814 6.5681 6.8254 6.8696 6.9264 6.8979 6.9955 6.9295 6.9478 7.0187 7.1985 7.2114 7.3628 7.3499 7.3553 7.3902 7.4286 7.4703 7.4597 7.4966 7.5089 10.6483 10.6665
0.0710 0.0423 0.3780 0.1102 0.1695 0.4911 1.0664 0.7487 0.7512 0.7777 2.5699 0.4822 1.6441 3.4846 0.7060 0.1127 2.8240 1.1959 2.8630 3.6561 1.4838 0.3697 0.6809 7.6965 33.8473 103.5344 26.2573 37.2765 94.6261 2.2027 3.0135 3.5461 9.6547 6.7522 1.3306 6.8891 4.2232 0.1292 3.6654 2.8103 1.5168 4.5023 2.4330 0.9316 4.0748 11.5360 7.6989 15.4042 6.4051 4.7525 0.5905 0.8661 22.7715 6.9226 0.7202 33.0952 11.0189 0.4706 2.0466 1.5461 13.2663 0.8442 7.5070 2.6573 2.7925 35.8919 44.2400 51.9086 1.6554 3.1455 55.4569 4.5479 0.0682 0.3114 41.0833 9.4834 31.4356 1.0777 69.4883 11.9468 41.4284 14.1682 2.5743 7.4792 0.9914 0.3276 1.1145 1.0105 1.5451 0.7018 0.9156 42.3107 1.6807 1.9020 21.3170 22.1887 13.3762 2.8804 16.5379 1.5174 11.8208 17.7202 19.5524 66.5521 109.5689 104.1931 11.5785 61.0086 42.0827 188.9123 2.4047 2.8632 37.1549 68.5130 65.1107 4.5829 253.9459 0.9171 81.8471 193.6395 36.8190 1.0856 161.8115 14.4979 98.8992 13.1987 4.9188 4.1047 7.3028 13.3376 52.8869 169.3150 8.3942 59.1166 12.1859 0.5390 8.9743 61.8774 62.0520 57.9688 59.8215 59.1938 8.8625 0.9097 0.6666 1.2283 0.5061 2.4493 113.1508 26.7702 4.5226 0.7495 71.5178 97.1820 174.8914 51.7842 12.0415 43.0142 323.2347 48.6198 162.7784 295.1701 36.9960 22.5661 80.2281 30.8914 81.3555 23.6605 34.9314 58.6327 44.7122 26.8176 16.5849 32.8567 29.3073 108.5505 56.7022 38.4879 24.6152 29.4525 27.8587 7.3736 4.2825 16.2093 11.2933 5.6430 5.3024 4.6893 8.5665 7.4866 113.4005 118.5574
4.2597 2.4582 0.8803 2.4183 0.6739 5.5297 3.2275 5.1670 2.1262 3.3598 2.1402 1.1296 0.9256 0.3736 0.1686 2.8279 2.8736 2.4581 1.5477 1.5389 1.9879 2.9650 0.5752 0.9852 2.8073 3.4430 1.0416 0.4021 4.3889 3.7110 3.5569 0.5486 1.8087 2.6310 1.8817 2.5885 3.7719 1.5773 5.3611 0.2861 1.3240 0.7449 2.7729 2.2136 0.5140 9.5892 6.3912 2.1308 1.4503 2.1530 0.7153 0.9517 3.4895 5.8058 6.2159 7.7720 5.9881 14.2553 4.0764 3.2664 12.5344 12.2214 2.1614 2.9732 12.7898 26.6979 4.7474 1.7367 4.4264 4.3176 6.9193 8.0454 11.2583 2.0031 3.0256 1.8992 2.3774 9.2612 13.8650 1.8979 1.6397 3.5731 0.5141 4.9000 3.9838 0.5964 2.1881 1.6920 13.5764 0.4370 0.3341 0.9859 4.5361 23.5321 15.0607 46.8015 39.0290 1.7455 5.1504 1.8777 0.5463 18.4506 5.5795 3.3340 15.5158 21.5826 5.5636 26.6320 43.3266 31.7035 1.9376 5.9772 31.8769 46.1704 30.5568 3.6765 27.2954 9.7095 33.0979 27.4205 26.1914 11.8192 4.6728 6.9488 23.6050 3.9146 12.6843 4.9314 15.9998 2.2904 52.6578 239.3267 1.5329 45.5235 11.3031 2.4193 0.4965 1.5518 12.8419 32.0107 25.5294 3.1203 2.6187 20.4989 19.5009 14.0492 3.1195 1.3666 124.4429 19.5033 21.8949 4.8827 6.3410 1.6201 358.9984 33.0331 146.2644 27.0029 569.9382 377.9014 213.9556 143.6305 30.9350 7.2517 135.2729 11.4776 38.8357 85.4211 29.0105 31.6419 111.2741 84.6775 120.0632 84.2115 41.0347 56.6015 67.8709 106.7644 54.3450 93.6818 155.9128 57.4271 32.7461 55.8424 49.1208 87.5890 102.0666 100.7574 57.8461 97.9466 110.4675 166.2730
0.7446 0.6989 0.7316 0.6884 0.7390 0.7420 0.5946 0.6521 0.7495 0.6980 0.7237 0.5444 0.7499 0.7310 0.7387 0.7175 0.3401 0.3398 0.6543 0.1686 0.7500 0.1908 0.2555 0.5657 0.7058 0.7442 0.6494 0.7479 0.7075 0.3722 0.7060 0.5351 0.2283 0.5229 0.4554 0.2325 0.4613 0.6011 0.2332 0.6319 0.4830 0.7304 0.3815 0.2479 0.7496 0.6978 0.2448 0.1789 0.5342 0.6757 0.7032 0.7489 0.4431 0.5249 0.7474 0.3238 0.4902 0.1547 0.6818 0.4789 0.2378 0.2386 0.7137 0.7100 0.2799 0.0338 0.7017 0.6782 0.2807 0.1886 0.2675 0.1778 0.0898 0.2907 0.5592 0.0969 0.6696 0.1857 0.3025 0.4523 0.7485 0.7289 0.3635 0.3583 0.6253 0.4721 0.5276 0.6697 0.1835 0.6070 0.3409 0.6243 0.0938 0.2300 0.0528 0.4403 0.1228 0.6879 0.5866 0.5570 0.4352 0.0851 0.7355 0.3240 0.6334 0.6881 0.7140 0.7449 0.1443 0.5025 0.5052 0.7449 0.5310 0.6032 0.7321 0.6649 0.5477 0.4253 0.3542 0.0595 0.3160 0.7196 0.0488 0.2028 0.1165 0.6445 0.4935 0.7486 0.5096 0.3720 0.2598 0.2752 0.7023 0.3972 0.6703 0.7156 0.5714 0.4749 0.5829 0.1994 0.3180 0.2598 0.7191 0.7465 0.7496 0.6515 0.7359 0.6428 0.3468 0.7448 0.6605 0.7324 0.2031 0.5107 0.3654 0.3128 0.2386 0.1766 0.4215 0.3346 0.3569 0.1726 0.3473 0.5609 0.2078 0.4107 0.2996 0.2277 0.7379 0.6579 0.1050 0.2085 0.2798 0.7498 0.4771 0.7331 0.4690 0.1640 0.3074 0.3881 0.3411 0.1723 0.7269 0.4066 0.6388 0.3148 0.2423 0.1714 0.2039 0.1206 0.3058 0.3055
0.8536 0.8228 0.8450 0.8155 0.8499 0.8519 0.7457 0.7894 0.8568 0.8221 0.8397 0.7050 0.8571 0.8446 0.8497 0.8355 0.5076 0.5073 0.7910 0.2886 0.8571 0.3205 0.4070 0.7226 0.8276 0.8533 0.7874 0.8557 0.8287 0.5425 0.8277 0.6971 0.3717 0.6867 0.6258 0.3773 0.6313 0.7508 0.3782 0.7744 0.6513 0.8442 0.5523 0.3973 0.8569 0.8220 0.3934 0.3036 0.6964 0.8065 0.8257 0.8564 0.6141 0.6884 0.8554 0.4892 0.6579 0.2680 0.8108 0.6476 0.3842 0.3853 0.8329 0.8304 0.4374 0.0654 0.8247 0.8082 0.4384 0.3174 0.4221 0.3020 0.1648 0.4504 0.7173 0.1766 0.8021 0.3133 0.4645 0.6228 0.8562 0.8432 0.5332 0.5276 0.7695 0.6414 0.6908 0.8022 0.3102 0.7554 0.5085 0.7687 0.1715 0.3739 0.1002 0.6114 0.2187 0.8151 0.7394 0.7155 0.6065 0.1568 0.8476 0.4894 0.7756 0.8153 0.8332 0.8538 0.2522 0.6689 0.6713 0.8538 0.6936 0.7525 0.8453 0.7987 0.7078 0.5968 0.5231 0.1122 0.4803 0.8370 0.0930 0.3372 0.2087 0.7838 0.6609 0.8562 0.6752 0.5422 0.4125 0.4316 0.8251 0.5686 0.8026 0.8342 0.7272 0.6439 0.7365 0.3325 0.4826 0.4124 0.8366 0.8548 0.8569 0.7890 0.8479 0.7825 0.5150 0.8537 0.7956 0.8455 0.3377 0.6761 0.5353 0.4765 0.3852 0.3002 0.5930 0.5014 0.5261 0.2944 0.5156 0.7187 0.3440 0.5823 0.4611 0.3709 0.8492 0.7936 0.1900 0.3451 0.4373 0.8570 0.6460 0.8460 0.6385 0.2819 0.4703 0.5592 0.5087 0.2940 0.8419 0.5781 0.7796 0.4788 0.3901 0.2926 0.3387 0.2153 0.4684 0.4681
298.150
1.00000
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66
8 6 6 6 6 6 16 6 6 6 8 6 6 6 6 6 8 6 6 6 6 7 6 6 7 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
15.99491 12.00000 12.00000 12.00000 12.00000 12.00000 31.97207 12.00000 12.00000 12.00000 15.99491 12.00000 12.00000 12.00000 12.00000 12.00000 15.99491 12.00000 12.00000 12.00000 12.00000 14.00307 12.00000 12.00000 14.00307 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783
10562.3005 44790.0809 50445.3999
0.99999 0.00242 0.00326 -0.00243 0.99999 0.00254 -0.00326 -0.00255 0.99999
1
0.00820 0.00193 0.00172
0.17087 0.04029 0.03578
12.18 24.96 35.04 45.82 56.14 63.37 77.12 86.43 90.21 102.92 131.16 154.23 175.27 185.01 197.71 212.93 270.09 297.19 303.62 314.67 354.81 363.78 394.01 409.03 421.27 428.73 468.72 471.76 482.31 529.82 538.42 585.55 617.09 631.54 641.00 654.43 666.11 667.70 680.90 699.53 708.55 736.10 756.76 762.85 782.89 824.53 840.65 856.41 875.45 927.13 933.88 947.42 981.11 1002.13 1004.16 1038.96 1067.20 1104.44 1120.32 1149.87 1163.01 1190.55 1218.45 1219.04 1273.03 1277.76 1299.73 1315.09 1325.92 1332.07 1337.65 1351.04 1359.28 1368.79 1371.55 1391.27 1392.78 1397.46 1429.59 1469.70 1479.67 1497.59 1513.10 1534.21 1549.25 1552.98 1571.98 1576.73 1589.81 1592.49 1599.96 1611.75 1612.41 1638.42 1639.01 1666.86 1700.70 1705.04 1731.38 1734.80 1764.54 1772.41 1783.95 1791.57 1840.07 1842.60 1844.70 1869.84 1873.81 1884.50 1901.37 1921.28 1926.03 1933.92 1941.56 1944.95 1959.12 1967.52 1983.05 1986.65 1999.78 2025.97 2032.03 2059.16 2065.65 2067.68 2075.09 2091.23 2102.84 2121.60 2123.85 2136.84 2145.82 2161.69 2169.47 2181.90 2223.13 2232.25 2261.25 2272.26 2289.24 2294.20 2296.31 2351.10 2361.85 2364.99 2371.33 2373.72 2383.05 2384.39 2396.97 2408.62 2427.77 2433.64 2514.93 2526.00 2552.70 2569.98 2597.51 2614.90 2619.92 2796.51 4442.60 4490.95 4505.68 4535.76 4551.71 4611.75 4614.18 4628.00 4650.64 4670.64 4689.58 4695.73 4708.03 4714.79 4727.06 4733.67 4755.89 4815.82 4818.84 4861.49 4866.84 4869.93 4882.38 4885.96 4893.13 4893.98 4905.26 4909.89 5922.06 5926.99
0.584177
0.613623
0.614567
0.519339
-1883.919384
-1883.889938
-1883.888994
-1883.984222
3.193963D-04
MUNgauss
RevisionA2.0
retrievium
27-Feb-2020
DUDE Oc6ccc(c2sc1cc(O)ccc1c2C(=O)c5ccc(N4CCN(C3CCCC3)CC4)cc5)cc6 301603 CHEMBL366928
RHF
6-31G(d)
(6D,10F)
C1
498.197715
|X|Y|Z|
67.086702 39.228430 152.277571
73.726639
33
|73.516695|
|25.094985|36.858105|
|14.116993|13.748408|36.858105|
|9.282075|7.947527|13.763370|36.858105|
|8.176604|6.820134|7.884705|13.709510|36.858105|
|6.023893|4.457644|5.044491|7.615969|12.868270|36.858105|
|5.082124|3.559403|4.153113|5.827602|6.815420|10.819440|388.023441|
|4.201832|2.836792|3.142770|4.052521|4.820632|7.578894|77.681779|36.858105|
|3.613114|2.370516|2.602489|3.197884|3.591579|4.895636|48.313692|13.720742|36.858105|
|3.256530|2.104415|2.263492|2.703505|3.039464|3.972763|33.545100|8.033567|13.821787|36.858105|
|2.906098|1.847740|1.979707|2.308979|2.526067|3.131720|26.366293|5.298614|8.160836|14.092545|73.516695|
|3.292242|2.128822|2.253669|2.677505|3.084693|4.040294|30.249832|6.938670|7.889920|13.616233|14.095607|36.858105|
|3.713452|2.442547|2.573246|3.114519|3.748275|5.165400|34.568049|7.944031|6.794399|7.905549|9.272666|13.851708|36.858105|
|4.292234|2.907742|3.128988|3.985785|5.035587|8.144326|52.229313|13.656677|7.812396|6.848247|8.193626|7.944236|13.648318|36.858105|
|5.174462|3.645962|3.898097|5.178899|7.469350|14.171130|52.414329|8.048124|5.168722|4.508203|6.075547|5.019764|7.388065|13.075949|36.858105|
|5.162465|3.558548|3.591836|4.389356|6.018783|7.494900|33.376250|5.044484|3.811876|3.616440|5.126047|4.244849|6.111445|7.400142|12.653355|36.858105|
|4.714226|3.151972|3.077060|3.589743|4.739432|5.579161|28.148745|4.395432|3.508854|3.459343|4.981427|4.172344|5.886746|6.240633|8.164400|15.879687|73.516695|
|5.380546|3.661209|3.708676|4.366410|5.424160|5.777920|27.664286|3.960678|3.157498|3.014345|4.434278|3.444370|4.535638|5.144897|7.344216|12.804018|14.448472|36.858105|
|5.106937|3.322396|3.212826|3.527550|4.167541|4.168288|21.735082|3.113831|2.604362|2.545341|3.855422|2.908583|3.652913|3.870002|4.943915|7.677894|12.138354|13.627446|36.858105|
|4.922355|3.095692|3.008107|3.182282|3.516504|3.410646|18.756292|2.646154|2.272500|2.224631|3.442400|2.492140|2.997515|3.139922|3.807819|5.073772|8.145954|7.898251|13.882613|36.858105|
|4.965371|3.118519|3.152289|3.331359|3.497600|3.367322|18.919560|2.625637|2.264721|2.193586|3.411607|2.411019|2.849704|3.031324|3.625851|4.428143|6.773420|6.766232|7.887782|13.575151|36.858105|
|4.514594|2.729772|2.751168|2.813539|2.855646|2.729953|16.060443|2.222042|1.964314|1.913028|3.033171|2.075718|2.379791|2.493508|2.870681|3.340134|5.321110|4.516634|5.172777|7.875398|13.578128|53.358707|
|4.194179|2.520007|2.618044|2.679924|2.634808|2.542458|15.466533|2.132716|1.910343|1.855504|2.969982|1.983987|2.230930|2.338607|2.626728|2.909721|4.606975|3.746109|3.927880|5.120263|7.787348|17.887244|36.858105|
|3.660381|2.148151|2.203020|2.222157|2.184471|2.114764|13.181060|1.829150|1.667859|1.634513|2.654693|1.740748|1.922517|1.984511|2.181449|2.395113|3.902761|2.939201|3.138930|3.958046|5.099840|10.628506|12.516690|36.858105|
|3.761168|2.159264|2.171040|2.136996|2.093143|1.986713|12.358292|1.694225|1.543326|1.506153|2.452310|1.597319|1.763036|1.829832|2.026565|2.230295|3.677728|2.700390|2.939833|3.698186|4.483170|9.045093|7.762741|13.114688|53.358707|
|3.293404|1.870145|1.875463|1.841961|1.804917|1.725192|10.923336|1.504961|1.387462|1.361152|2.238343|1.437670|1.567072|1.612328|1.758450|1.914781|3.202082|2.251060|2.434297|2.943476|3.372495|6.102714|5.048867|7.841404|17.792496|36.858105|
|3.279867|1.827227|1.807548|1.746489|1.706329|1.612455|10.236571|1.398540|1.290270|1.261556|2.079968|1.326372|1.442709|1.490298|1.629187|1.767997|2.980834|2.047118|2.218449|2.630904|2.908736|4.985749|3.852057|5.004355|10.373806|12.340708|36.858105|
|2.922920|1.623471|1.617365|1.565114|1.521973|1.447348|9.333597|1.277135|1.188929|1.164228|1.934204|1.216553|1.309917|1.348703|1.457376|1.560427|2.639120|1.775521|1.892666|2.185620|2.397463|3.944268|3.119573|3.944848|6.936938|7.693956|12.301500|36.858105|
|2.789309|1.567964|1.582977|1.550123|1.505675|1.447426|9.398671|1.294375|1.210589|1.189020|1.980536|1.241617|1.330878|1.364517|1.462721|1.557404|2.622570|1.772961|1.869717|2.153321|2.399480|3.957517|3.275699|4.322884|6.942593|7.925172|7.734439|12.362330|36.858105|
|3.069186|1.742851|1.773731|1.746207|1.691601|1.626148|10.473482|1.441299|1.339545|1.312538|2.172672|1.374383|1.482898|1.526187|1.646016|1.758637|2.929468|2.037400|2.144167|2.515312|2.900313|4.978882|4.386203|6.426331|10.316707|12.415376|7.909789|7.846924|12.454524|36.858105|
|3.982565|2.285124|2.243611|2.202312|2.198993|2.073291|12.658601|1.739078|1.572368|1.537715|2.489469|1.645809|1.835956|1.902975|2.134302|2.410403|4.017113|2.955451|3.374641|4.442538|5.108115|10.593616|6.731945|8.037769|17.843459|7.876495|6.422028|4.273324|3.973049|5.003079|36.858105|
|4.705529|2.751608|2.686915|2.644286|2.660154|2.470246|14.630497|1.992064|1.769068|1.715996|2.741597|1.845413|2.097446|2.206876|2.544592|2.937589|4.800834|3.780599|4.429961|6.350145|7.824595|17.783259|7.952044|6.746273|10.581093|5.062695|4.407427|3.277584|3.114913|3.839893|12.535062|36.858105|
|5.211910|3.391895|3.614753|4.010426|4.150106|4.069001|22.470289|3.080728|2.603811|2.476414|3.797600|2.696095|3.222271|3.547530|4.328232|5.015154|7.130649|7.889275|6.897343|7.952732|13.685284|10.558707|6.669733|4.376882|5.117693|2.935853|2.554791|2.173898|2.207251|2.655738|3.935949|5.349045|36.858105|
|5.434495|3.699752|3.988795|4.783172|5.377161|5.610852|28.283966|3.910458|3.147103|2.949013|4.380994|3.254812|4.095516|4.740277|6.315696|7.532507|9.417815|13.752629|7.982198|6.905673|7.888465|6.977099|4.496539|3.328428|4.035823|2.426272|2.169472|1.882770|1.902168|2.225620|3.131199|4.038597|13.741646|36.858105|
|9.390742|7.957485|6.894978|7.976917|13.649698|7.621307|34.434088|3.878763|3.037613|2.676375|4.022551|2.777027|3.362401|4.223777|6.012196|5.829651|8.892195|5.253216|4.399970|3.650017|3.444673|3.849088|2.531955|2.128934|2.833050|1.799334|1.722576|1.526869|1.492279|1.664035|2.236739|2.721052|3.813062|4.707474|36.858105|
|14.463251|13.722910|7.936745|6.888508|7.878250|5.050094|26.653126|3.060916|2.514605|2.248484|3.468334|2.313636|2.710363|3.243151|4.224277|4.271633|6.833969|4.214964|3.837716|3.398659|3.250612|3.765079|2.480127|2.112487|2.876339|1.830787|1.781280|1.575308|1.521527|1.687807|2.281001|2.769159|3.470272|3.948168|13.814931|36.858105|
|35.761344|10.003063|7.779462|4.985468|4.151877|3.147653|19.493443|2.260250|1.962816|1.765919|2.819573|1.771568|1.978590|2.278809|2.700026|2.656767|4.293447|2.788487|2.633367|2.578345|2.659644|3.346911|2.333184|2.046926|2.865169|1.850821|1.847209|1.657591|1.584610|1.742752|2.193168|2.559075|2.817302|2.889634|4.435671|6.054705|0.500000|
|12.720711|8.900103|17.689845|8.918468|5.623353|4.108951|25.924455|2.816488|2.396088|2.094024|3.303273|2.065861|2.314530|2.758879|3.297003|3.048634|4.708618|3.189988|2.818495|2.714430|2.906379|3.559009|2.553811|2.173231|2.926615|1.869395|1.809308|1.631768|1.599199|1.789190|2.184182|2.571007|3.316757|3.511528|4.961246|5.639064|0.229806|0.500000|
|7.495666|5.661462|8.966848|17.718353|8.907120|7.020965|45.096950|4.270528|3.406544|2.827819|4.306977|2.741740|3.129655|4.009145|4.900116|4.002937|5.824274|4.000606|3.215701|2.950414|3.167591|3.692840|2.660072|2.207539|2.850281|1.812965|1.706019|1.541245|1.541645|1.741281|2.119188|2.507419|3.909967|4.602524|5.655494|4.960236|0.116977|0.216680|0.500000|
|3.490223|2.269289|2.511089|3.045036|3.298005|4.256935|44.517380|8.814226|17.744013|8.958970|13.281049|5.628547|4.913271|5.572993|4.207576|3.216061|5.289377|2.752810|2.311922|2.053429|2.064917|2.472971|1.784054|1.569836|1.985842|1.318883|1.231570|1.141199|1.162441|1.281368|1.477495|1.650449|2.362858|2.787222|2.794766|2.365304|0.053104|0.065163|0.091508|0.500000|
|2.753648|1.739461|1.846522|2.130018|2.333407|2.848376|22.924007|4.456922|6.072212|9.999231|35.769897|7.803093|5.003444|4.171191|3.162638|2.763408|4.854639|2.408271|2.124605|1.902689|1.874872|2.278474|1.635815|1.470873|1.847548|1.243192|1.153907|1.074008|1.101030|1.205455|1.380170|1.512493|2.063810|2.359220|2.123034|1.842698|0.041693|0.048188|0.061548|0.152085|0.500000|
|3.015947|1.924044|2.016104|2.344803|2.663276|3.334339|24.390081|4.984045|5.631647|8.879483|12.783933|17.691410|8.954496|5.644434|4.058480|3.689211|6.658568|3.099597|2.712133|2.356435|2.267081|2.691404|1.891342|1.679712|2.096985|1.396436|1.287441|1.184447|1.211305|1.335521|1.587967|1.761948|2.484014|2.917026|2.454048|2.085738|0.045148|0.051724|0.066357|0.124132|0.232355|0.500000|
|3.657104|2.386135|2.466738|2.922719|3.523453|4.585286|28.586415|5.640830|4.913349|5.633420|7.486372|8.963768|17.744335|8.872640|6.644325|6.690000|12.460682|4.959671|4.115606|3.301014|3.045972|3.432466|2.322657|2.003713|2.498491|1.628657|1.495287|1.350745|1.370326|1.527816|1.932079|2.212111|3.355016|4.234769|3.286691|2.677070|0.053857|0.061563|0.080128|0.106890|0.117266|0.216255|0.500000|
|4.836603|3.102201|2.928704|3.177082|3.808321|3.839351|20.439119|2.969586|2.512532|2.485932|3.783253|2.868714|3.589752|3.702360|4.596312|7.182683|13.681957|8.927567|17.748895|8.968678|5.624113|5.709294|3.285695|2.752377|3.578283|2.231834|2.065946|1.775797|1.743427|1.967142|3.037392|3.814470|4.967310|5.675336|4.201399|3.680347|0.068725|0.071405|0.080041|0.061927|0.058300|0.075180|0.114938|0.500000|
|4.557611|2.785818|2.660329|2.751152|3.006336|2.904669|16.466888|2.331394|2.038972|2.014168|3.158711|2.250714|2.652951|2.726222|3.206371|4.141919|7.061349|5.636260|8.990450|17.742768|8.878486|9.861687|4.703506|3.922330|5.181468|3.072346|2.773506|2.275794|2.214738|2.558817|4.857258|6.697854|5.652517|4.971598|3.185110|3.050843|0.066389|0.067499|0.070993|0.051560|0.048803|0.059951|0.081418|0.216859|0.500000|
|4.550828|2.723902|2.874138|2.897321|2.764346|2.612054|15.956837|2.150112|1.918293|1.838018|2.942471|1.938780|2.174180|2.321125|2.627544|2.841261|4.449437|3.608010|3.647203|4.530149|6.667570|12.265489|17.451622|8.899509|9.473468|4.690713|3.766206|3.093929|3.215366|4.280516|5.822820|7.015976|6.485384|4.447250|2.627766|2.610404|0.071234|0.079151|0.080358|0.050129|0.044710|0.050919|0.061961|0.085078|0.113719|0.500000|
|3.954441|2.410191|2.543780|2.672418|2.645904|2.625318|16.120179|2.261365|2.033967|1.987532|3.176516|2.133645|2.394111|2.487673|2.750683|3.018053|4.738607|3.871869|3.917062|4.881860|7.253559|12.508103|17.596244|8.943763|7.685941|4.185434|3.253957|2.752794|2.956770|3.854912|5.028008|5.722861|7.065798|4.792398|2.492687|2.387858|0.061090|0.068722|0.074912|0.052537|0.048669|0.056565|0.069207|0.090621|0.121097|0.300544|0.500000|
|3.472991|2.032635|2.111641|2.130680|2.067724|2.010210|12.757222|1.766500|1.623913|1.588778|2.597327|1.676461|1.831412|1.891923|2.055368|2.209067|3.593195|2.654406|2.753951|3.326415|4.197504|7.728052|8.987783|17.616364|12.466996|7.184728|4.690884|3.980785|4.662195|7.412060|5.751012|5.023224|3.882926|3.038786|1.991675|1.976189|0.054479|0.058590|0.059577|0.042734|0.039925|0.044950|0.052516|0.067641|0.090187|0.220500|0.216422|0.500000|
|3.382784|1.992524|2.031979|2.070838|2.068476|2.033106|12.709686|1.792830|1.644936|1.630156|2.654754|1.750964|1.928310|1.959505|2.130244|2.360789|3.895692|2.875120|3.120389|3.929709|4.817312|9.511512|8.885451|17.411991|12.257044|6.969953|4.545737|3.683866|4.088380|5.670478|7.134675|5.860838|4.057114|3.176925|2.024567|1.988820|0.052200|0.055240|0.057096|0.042848|0.041111|0.047340|0.056359|0.076966|0.110981|0.174215|0.219597|0.301153|0.500000|
|3.077883|1.757013|1.756548|1.740859|1.725722|1.666813|10.568268|1.472298|1.363029|1.347461|2.220639|1.431191|1.556605|1.585172|1.716820|1.881398|3.174795|2.201111|2.405455|2.905765|3.247362|5.788720|4.599091|6.986321|12.331596|17.372852|8.815733|6.510801|7.005244|8.899864|7.105803|4.637465|2.797078|2.339508|1.725072|1.740753|0.047752|0.048291|0.047575|0.035900|0.034412|0.038851|0.045219|0.061845|0.085746|0.113351|0.110532|0.172869|0.205564|0.500000|
|3.224696|1.793096|1.753855|1.695411|1.673403|1.582422|10.005895|1.372358|1.265877|1.241799|2.046927|1.311040|1.428218|1.469310|1.607336|1.759343|2.994239|2.029902|2.233993|2.652396|2.847953|4.816645|3.529301|4.405498|8.644430|8.669849|17.576537|8.676915|5.850822|5.713026|6.426727|4.360065|2.460621|2.113477|1.707088|1.767185|0.050052|0.048389|0.045698|0.033493|0.031613|0.035443|0.041327|0.058463|0.079432|0.093892|0.083732|0.110816|0.116748|0.221424|0.500000|
|3.585975|1.979270|1.952609|1.863348|1.804241|1.684177|10.651267|1.439792|1.321696|1.283684|2.110373|1.344821|1.467692|1.529842|1.685901|1.823866|3.057508|2.117737|2.282712|2.702923|3.013795|5.129536|3.945172|4.825219|10.153584|8.863741|17.559680|8.738866|6.035761|6.585171|6.434770|4.703273|2.664640|2.256519|1.825298|1.909033|0.056369|0.054582|0.050372|0.035094|0.032403|0.036071|0.042087|0.058753|0.078293|0.111794|0.090901|0.125723|0.116075|0.175698|0.302829|0.500000|
|2.737218|1.517771|1.503696|1.457324|1.426027|1.360500|8.795412|1.208407|1.128665|1.109083|1.847732|1.160276|1.245912|1.276813|1.374262|1.473712|2.511855|1.663091|1.780933|2.040503|2.195358|3.550485|2.739511|3.379251|5.715014|5.925773|8.662133|17.570056|8.710866|5.740339|3.770604|2.939358|1.987009|1.743196|1.437825|1.482418|0.042962|0.041992|0.039777|0.030100|0.028565|0.031488|0.035761|0.046880|0.059545|0.074581|0.068199|0.093305|0.090735|0.157393|0.224176|0.179946|0.500000|
|2.962835|1.631640|1.626777|1.561151|1.505900|1.423398|9.217167|1.251959|1.165584|1.136251|1.889615|1.181116|1.269819|1.314334|1.421729|1.511064|2.550203|1.710031|1.806695|2.064647|2.266111|3.662643|2.901470|3.518299|6.052156|5.896128|8.754348|17.562751|8.763659|6.371142|3.780328|3.045611|2.085101|1.818177|1.509820|1.568847|0.046988|0.045937|0.042736|0.031189|0.029073|0.031856|0.036197|0.047099|0.059164|0.082158|0.071336|0.100026|0.089419|0.136333|0.183770|0.229531|0.304164|0.500000|
|2.620182|1.479176|1.490512|1.469444|1.438669|1.393463|9.064756|1.258563|1.181614|1.167257|1.949190|1.222849|1.307103|1.330292|1.417912|1.514226|2.565036|1.716404|1.818423|2.088203|2.297449|3.760021|3.062424|4.030037|6.182256|6.839133|6.335942|8.773656|17.530226|8.853904|3.712004|2.915410|2.104100|1.826643|1.427866|1.447270|0.041155|0.041603|0.040591|0.031474|0.030203|0.033296|0.037516|0.047387|0.060105|0.081451|0.078275|0.118500|0.111893|0.199161|0.149680|0.135512|0.224046|0.175978|0.500000|
|2.674858|1.500083|1.522422|1.488897|1.437661|1.383043|9.061117|1.244743|1.168910|1.146151|1.916410|1.190204|1.269181|1.303130|1.390528|1.466546|2.467142|1.655358|1.725988|1.960447|2.182184|3.518833|2.929461|3.697195|5.658034|5.649865|5.663094|8.652120|17.567091|8.695627|3.317620|2.728269|2.046446|1.781469|1.418462|1.447260|0.042442|0.043000|0.041339|0.031310|0.029562|0.032242|0.036119|0.044774|0.055474|0.081498|0.074768|0.113758|0.096513|0.140461|0.125655|0.136793|0.190530|0.222007|0.303172|0.500000|
|3.246245|1.836867|1.882467|1.839998|1.760068|1.678881|10.832891|1.475744|1.367874|1.330871|2.200058|1.385444|1.495926|1.553269|1.682194|1.782093|2.946055|2.065647|2.146085|2.501256|2.926400|4.965727|4.488661|6.110628|9.738938|8.862967|6.899578|6.776154|8.789803|17.516768|4.717017|3.836303|2.735788|2.284858|1.722132|1.756612|0.051615|0.053246|0.051142|0.036457|0.033767|0.037199|0.042545|0.054359|0.069579|0.129644|0.108374|0.204972|0.139137|0.174600|0.138862|0.186450|0.137499|0.176593|0.173792|0.215237|0.500000|
|2.939688|1.685758|1.729154|1.722757|1.674231|1.627957|10.540615|1.462764|1.365477|1.343830|2.229075|1.408810|1.514277|1.549352|1.657562|1.765773|2.937377|2.042912|2.134392|2.490755|2.888104|4.909212|4.460548|6.654057|8.807561|8.636367|5.627547|5.623494|8.727671|17.575726|4.464617|3.579018|2.678105|2.245074|1.633755|1.639235|0.046302|0.048343|0.048055|0.036253|0.034421|0.038136|0.043349|0.054270|0.069831|0.117626|0.113950|0.235830|0.173053|0.216285|0.125850|0.135023|0.127256|0.132357|0.218626|0.199088|0.301249|0.500000|
|3.993555|2.246706|2.174794|2.100125|2.089094|1.948874|11.959062|1.630930|1.477983|1.441800|2.342653|1.535345|1.705572|1.772717|1.987553|2.229894|3.752049|2.675066|3.042965|3.851315|4.204821|7.702944|5.014783|5.750304|12.460537|7.232616|7.439347|4.636532|3.978797|4.679658|17.610833|8.979249|3.372751|2.786421|2.152048|2.233486|0.061152|0.059069|0.055786|0.038750|0.036052|0.041159|0.049679|0.077805|0.118006|0.130469|0.110054|0.127923|0.144337|0.177038|0.225630|0.219544|0.114811|0.115095|0.102020|0.092335|0.124142|0.111549|0.500000|
|3.646857|2.106357|2.065033|2.053378|2.080928|1.993666|12.212144|1.703037|1.548168|1.528956|2.480822|1.649201|1.836067|1.876349|2.083338|2.375476|4.014733|2.890075|3.364478|4.431523|4.822113|9.479811|5.849240|7.139060|12.265327|7.003619|5.608775|3.965745|3.776160|4.581116|17.407809|8.889308|3.679942|2.994248|2.121480|2.135490|0.055468|0.055475|0.054983|0.040277|0.038412|0.044541|0.054175|0.085551|0.140967|0.133588|0.131576|0.144420|0.211581|0.210039|0.166802|0.143666|0.101131|0.095270|0.102703|0.087223|0.114386|0.118641|0.301148|0.500000|
|4.793953|2.799647|2.662386|2.617599|2.695440|2.495531|14.605087|1.996750|1.767450|1.720091|2.741176|1.863015|2.131602|2.234451|2.595956|3.073650|5.123748|3.940082|4.922468|7.258634|7.302440|12.416621|5.718158|5.027805|7.687966|4.193866|3.862940|2.944558|2.756754|3.248311|8.936262|17.639530|4.908777|3.955675|2.836225|2.896018|0.071170|0.069651|0.067868|0.045626|0.042097|0.049502|0.063060|0.120941|0.241916|0.142751|0.127781|0.110100|0.131417|0.111478|0.111232|0.113016|0.075375|0.076279|0.072881|0.067588|0.089045|0.084660|0.216391|0.218464|0.500000|
|5.293893|3.053726|2.978163|2.854688|2.800911|2.532972|15.005652|1.999749|1.768484|1.695467|2.708626|1.802660|2.044708|2.186970|2.544109|2.874349|4.643450|3.650156|4.081407|5.407346|6.729419|12.317236|7.065935|5.851614|9.494471|4.700985|4.320672|3.256904|3.051347|3.738150|8.890335|17.459359|5.212077|3.988250|2.863065|2.988739|0.080668|0.079996|0.074781|0.046109|0.041268|0.047466|0.059122|0.097777|0.148584|0.206814|0.143371|0.131053|0.134076|0.114104|0.115314|0.136461|0.080122|0.086666|0.077568|0.075498|0.108523|0.094982|0.219224|0.174047|0.301895|0.500000|
|5.022553|3.223320|3.550754|3.900197|3.810027|3.724745|21.659039|2.928636|2.517838|2.378737|3.692304|2.535292|2.945862|3.245249|3.809487|4.098923|5.963092|5.649380|4.969113|5.638712|8.874410|9.555009|7.496526|4.710825|5.323117|3.044545|2.614908|2.247385|2.315669|2.831276|3.845949|4.964358|17.769436|8.985100|3.407239|3.167275|0.077126|0.093643|0.109946|0.064395|0.055542|0.064981|0.083304|0.107844|0.123839|0.223271|0.233226|0.120783|0.116807|0.079272|0.068591|0.076077|0.056467|0.060196|0.060778|0.060077|0.082481|0.079960|0.091447|0.097967|0.120179|0.139679|0.500000|
|5.374617|3.716150|4.234907|5.441647|5.959265|6.698882|34.089711|4.615682|3.613040|3.282214|4.808072|3.531379|4.419611|5.422212|7.140478|6.904449|8.605328|8.918498|5.657463|4.971571|5.642576|5.668479|3.928751|2.996805|3.633258|2.226480|2.001682|1.765278|1.794875|2.087639|2.743066|3.398484|8.978315|17.748656|4.706683|3.861440|0.080433|0.104091|0.154584|0.088628|0.070817|0.085761|0.120169|0.124412|0.107885|0.111395|0.118356|0.078267|0.079126|0.059441|0.053819|0.057889|0.045413|0.047682|0.047817|0.047172|0.059990|0.058775|0.068673|0.072679|0.091305|0.095232|0.219116|0.500000|
|7.591256|5.663769|4.964625|5.661918|8.900455|7.050017|32.427674|3.938310|3.091392|2.777402|4.147852|2.945345|3.630824|4.482856|6.396769|6.676939|11.000464|5.431283|4.663420|3.693055|3.332781|3.710681|2.409380|2.046216|2.719190|1.737983|1.662916|1.474718|1.441349|1.599817|2.168097|2.617806|3.584958|4.465655|17.729483|8.979184|0.101159|0.107685|0.124159|0.077763|0.061230|0.072506|0.100446|0.130640|0.090572|0.068111|0.066246|0.052921|0.054764|0.046726|0.046120|0.048553|0.038796|0.040305|0.038552|0.037962|0.045592|0.043751|0.057920|0.057937|0.077061|0.074857|0.087455|0.120802|0.500000|
|13.291385|8.951216|5.657393|4.962037|5.610839|4.106034|22.609604|2.709313|2.274280|2.070065|3.225111|2.145887|2.493184|2.894816|3.650801|3.843143|6.463190|3.792024|3.654520|3.267522|3.040659|3.585036|2.335257|2.023461|2.792608|1.791769|1.762575|1.556901|1.491069|1.640218|2.244468|2.699669|3.118178|3.454370|8.896830|17.740984|0.152130|0.124287|0.107682|0.059499|0.047971|0.054416|0.069391|0.100835|0.083863|0.067548|0.061973|0.052336|0.053230|0.047508|0.049016|0.052434|0.040930|0.043054|0.039491|0.039311|0.047167|0.044053|0.061813|0.058668|0.079994|0.080403|0.078715|0.091746|0.215292|0.500000|
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