Version2.2 2021-02-10T17:25:40Z 10.1021/jm300687e Gaussian16 RevisionB.01 SBUNGAY 16-Nov-2020 #N HF/6-31G(d) OPT=(MaxStep=1) FREQ IOp(6/10=2,6/11=2,6/12=2) DUDE Cc1ccc2c(cc(=O)oc2c1)CSc3nc4c(c(c(s4)C)C)c(=O)n3C(C)C C36812067 RHF 6-31G(d) (6D,7F) Cc1ccc2c(cc(=O)oc2c1)CSc3nc4c(c(c(s4)C)C)c(=O)n3C(C)C C01[X(C22H22N2O3S2)] 147 C1 487 Cc1ccc2c(c1)oc(=O)cc2CSc1nc2sc(c(c2c(=O)n1C(C)C)C)C Cc1ccc2c(c1)oc(=O)cc2CSc1nc2sc(c(c2c(=O)n1C(C)C)C)C CC(C)N1C(=O)c2c(C)c(C)sc2N=C1SCC3=CC(=O)Oc4cc(C)ccc34 InChIKey=QYAHSFHODIVGOE-UHFFFAOYSA-N InChI=1S/C22H22N2O3S2/c1-11(2)24-21(26)19-13(4)14(5)29-20(19)23-22(24)28-10-15-9-18(25)27-17-8-12(3)6-7-16(15)17/h6-9,11H,10H2,1-5H3 InChI=1/C22H22N2O3S2/c1-11(2)24-21(26)19-13(4)14(5)29-20(19)23-22(24)28-10-15-9-18(25)27-17-8-12(3)6-7-16(15)17/h6-9,11H,10H2,1-5H3 Cc1ccc2c(cc(=O)oc2c1)CSc3nc4c(c(c(s4)C)C)c(=O)n3C(C)C C01[X(C22H22N2O3S2)] 147 C01 487 Cc1ccc2c(c1)oc(=O)cc2CSc1nc2sc(c(c2c(=O)n1C(C)C)C)C O=C1C=C(CS[C]2[N][C]3SC(=[C]([C]3C(=O)N2C(C)C)C)C)[C]2[C]([CH][C]([CH][CH]2)C)O1 C[C]1[CH][CH][C]2[C]([CH]1)OC(=O)C=C2CS[C]3[N][C]4SC(=C(C)[C]4C(=O)N3C(C)C)C InChIKey=QYAHSFHODIVGOE-UHFFFAOYSA-N InChI=1S/C22H22N2O3S2/c1-11(2)24-21(26)19-13(4)14(5)29-20(19)23-22(24)28-10-15-9-18(25)27-17-8-12(3)6-7-16(15)17/h6-9,11H,10H2,1-5H3 InChI=1/C22H22N2O3S2/c1-11(2)24-21(26)19-13(4)14(5)29-20(19)23-22(24)28-10-15-9-18(25)27-17-8-12(3)6-7-16(15)17/h6-9,11H,10H2,1-5H3 2989.6446862186 -1974.4654394 1-A 17510.0599 112 375 487 |A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A| -91.98336 -91.97315 -20.63467 -20.54473 -20.53819 -15.64321 -15.58058 -11.38718 -11.38576 -11.37201 -11.32788 -11.31857 -11.29721 -11.29230 -11.29068 -11.26788 -11.26779 -11.26307 -11.26159 -11.25529 -11.25194 -11.24387 -11.24336 -11.24119 -11.23782 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9.97099
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298.150 1.00000 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 6 6 6 6 6 6 6 6 8 8 6 6 6 16 6 7 6 6 6 6 16 6 6 6 8 7 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 15.99491 15.99491 12.00000 12.00000 12.00000 31.97207 12.00000 14.00307 12.00000 12.00000 12.00000 12.00000 31.97207 12.00000 12.00000 12.00000 15.99491 14.00307 12.00000 12.00000 12.00000 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783
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MUNgauss RevisionA2.1 retrievium 10-Feb-2021 DUDE Cc1ccc2c(cc(=O)oc2c1)CSc3nc4c(c(c(s4)C)C)c(=O)n3C(C)C C36812067 RHF 6-31G(d) (6D,10F) C1 426.107186 |X|Y|Z| 114.818074 50.246968 42.451062
62.565688 21 6 7 8 16 16 2 1 2
|36.858105| |12.621886|36.858105| |7.551396|13.606832|36.858105| |5.026367|7.899595|13.872885|36.858105| |4.407829|6.772993|7.890479|13.608388|36.858105| |3.294007|4.457134|5.030124|7.493179|13.012418|36.858105| |2.940051|3.804184|3.949968|5.120182|7.902800|14.283609|36.858105| |3.118805|3.992815|3.806509|4.513584|6.743758|7.768625|13.002550|36.858105| |2.712326|3.297162|3.104837|3.527199|4.753803|5.379394|8.108873|16.092356|73.516695| |3.932825|5.289900|4.647644|5.233419|7.961079|6.861832|7.966242|14.114343|15.494873|73.516695| |5.026145|7.945496|6.933152|7.999018|13.734793|7.818432|6.931363|8.007570|9.855416|25.038951|36.858105| |7.569766|13.805722|7.965546|6.886508|7.852901|5.100829|4.607545|5.289936|7.507044|14.545850|13.728869|36.858105| |2.824417|3.617696|4.304224|6.239739|7.357094|12.616413|7.730439|4.963933|7.036052|7.901584|4.972381|3.800387|36.858105| 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|1.580173|1.758350|1.993791|2.251545|2.171160|2.388073|2.175592|1.866869|3.075071|3.153738|1.879416|1.718837|2.940271|21.301210|4.085386|6.782902|7.663287|8.238382|14.147480|36.858105| |1.773961|2.011833|2.307853|2.678857|2.600536|2.930061|2.623957|2.193665|3.566825|3.673972|2.201098|1.977434|3.774638|25.473395|4.938356|9.574859|11.051870|7.451362|7.355372|10.829199|388.023441| |1.437265|1.578721|1.766392|1.958002|1.893443|2.054530|1.901036|1.662745|2.767211|2.821400|1.669716|1.543914|2.443354|17.326802|3.097964|4.948790|4.835440|5.028407|7.368628|12.673869|48.519416|36.858105| |1.457216|1.599819|1.797686|1.991410|1.912834|2.066418|1.900488|1.661662|2.757510|2.829395|1.681788|1.557953|2.463009|19.333904|3.633767|5.194762|5.056710|7.338519|12.646388|7.483874|33.330503|5.940163|36.858105| |1.817777|2.057598|2.369918|2.736862|2.626872|2.911410|2.588087|2.180505|3.534320|3.686213|2.223627|2.009347|3.682903|33.527977|7.880777|9.163581|7.936485|13.174352|7.293671|5.132941|34.502353|3.704689|6.015677|36.858105| |1.686304|1.879849|2.136068|2.407603|2.310168|2.510561|2.271912|1.958854|3.209773|3.334168|1.998814|1.832176|3.035806|27.222931|5.434489|6.436169|5.402419|8.097816|6.252473|4.393813|27.597043|3.387333|6.344741|15.863468|73.516695| |2.041971|2.360051|2.750473|3.273331|3.163455|3.572338|3.099097|2.549617|4.064872|4.292164|2.612217|2.317616|4.674221|50.000412|13.913626|11.037664|7.148178|7.929926|5.005639|4.069573|30.888059|3.084651|4.179253|13.498207|14.926323|53.358707| |2.048914|2.348024|2.691873|3.126128|3.038818|3.333353|2.951813|2.498349|4.009389|4.248955|2.573803|2.310337|4.017195|44.984247|7.612352|6.999813|4.580361|5.044111|3.746489|3.129287|23.038869|2.518974|3.426491|7.670016|12.437745|17.352709|36.858105| |2.053497|2.303475|2.652943|2.965221|2.769615|2.880765|2.538766|2.217772|3.567405|3.878517|2.384491|2.209052|3.330276|33.652757|5.378593|5.584876|3.851722|4.338841|3.440828|2.876029|20.516391|2.369997|3.292646|6.203137|11.480252|10.352394|12.465232|36.858105| |1.801962|2.036357|2.264568|2.579855|2.586411|2.869582|2.667238|2.298912|3.783016|3.850819|2.264491|2.038894|3.337303|33.645557|5.379543|5.587360|3.854539|4.342297|3.443687|2.878233|20.530911|2.371745|3.295359|6.205800|11.475728|10.352600|12.465245|7.438255|36.858105| |17.549559|8.863328|6.729029|4.612536|3.959047|3.044263|2.711065|2.828928|4.415171|6.151727|4.313574|5.899247|2.677126|18.539080|2.223349|2.889864|1.889838|1.767791|1.587208|1.559735|12.305172|1.416768|1.461407|1.830084|3.041379|2.797671|2.092169|2.133707|1.834283|0.500000| |17.592989|8.838850|5.562710|4.172538|3.943255|3.047197|2.819626|3.096207|4.885757|7.026405|4.753130|7.261270|2.584891|17.192594|2.053007|2.706333|1.768889|1.640383|1.481651|1.470568|11.690284|1.345185|1.360422|1.679469|2.783177|2.556283|1.893057|1.884694|1.690612|0.301529|0.500000| |17.550045|8.862811|6.735212|4.614248|3.958816|3.045716|2.712171|2.828811|4.414602|6.148641|4.311411|5.894111|2.680573|17.607638|2.154985|2.881241|1.892464|1.745076|1.580640|1.578229|12.609554|1.444405|1.443347|1.767249|2.913343|2.669151|1.941719|1.953765|1.708234|0.302222|0.301522|0.500000| |7.013321|8.876890|17.713644|8.981164|5.629241|4.088386|3.291977|3.143234|4.702900|6.545253|4.982875|5.658936|3.767261|25.306273|3.032306|3.986505|2.536633|2.308244|2.026835|1.999227|16.250418|1.777511|1.816381|2.359648|3.807806|3.668863|2.635112|2.673151|2.203097|0.191168|0.140484|0.191460|0.500000| |4.108193|5.640501|9.007516|17.748768|8.877137|6.830049|4.641762|3.892462|5.576259|7.480225|5.669054|4.961655|6.996155|43.097122|4.750226|6.226693|3.605765|3.103108|2.587762|2.546682|21.847619|2.176732|2.226388|3.150788|4.832355|5.188509|3.518709|3.340566|2.809092|0.108893|0.096150|0.108885|0.218101|0.500000| |2.523254|3.136879|3.272281|4.103044|5.583938|9.007155|17.761402|8.855977|13.066676|10.167960|4.989654|3.661933|7.060384|36.391522|3.855697|5.172591|3.049274|2.626498|2.243692|2.242900|19.274517|1.958357|1.949314|2.639732|4.111737|4.266153|2.952586|2.487376|2.738910|0.065450|0.067624|0.065489|0.078432|0.108649|0.500000| |6.931975|8.872463|5.635073|4.961526|5.635932|4.181247|4.045897|4.933649|7.448691|13.483672|8.987560|17.739641|3.213021|20.439135|2.321701|3.051921|1.945322|1.775452|1.582534|1.573432|12.740234|1.426092|1.436311|1.817401|2.973922|2.819828|2.079802|1.994158|1.869356|0.151243|0.219945|0.151071|0.123755|0.107711|0.092216|0.500000| |2.902825|3.697920|4.601374|6.746192|6.836431|8.829726|5.814276|4.193276|6.072034|7.064722|4.625734|3.713836|17.674998|56.374525|6.635385|10.137296|5.041015|3.879160|3.124151|3.156204|29.831779|2.612511|2.553455|3.711806|5.398297|6.176852|3.772732|3.260721|3.083361|0.076173|0.072626|0.078148|0.114733|0.235074|0.146750|0.086550|0.500000| |2.473311|3.067775|3.502544|4.676837|5.508156|8.899542|7.374154|4.716330|7.012176|7.108675|4.177097|3.267330|17.677815|56.513277|6.453707|9.592108|4.851360|3.784028|3.056839|3.078091|28.759336|2.557407|2.512755|3.650104|5.335138|6.089432|3.762560|3.062703|3.275097|0.065098|0.063954|0.065767|0.086912|0.140878|0.221731|0.079275|0.303516|0.500000| |1.457995|1.594586|1.788272|1.967895|1.884498|2.019327|1.857920|1.634430|2.712973|2.795847|1.664078|1.549048|2.380942|16.605560|2.906724|4.653996|4.380568|4.366328|5.804682|8.868541|44.679427|17.546119|4.824585|3.322520|5.400522|3.877446|2.352911|2.249510|2.183880|0.039861|0.037817|0.040978|0.050320|0.060841|0.052683|0.039721|0.071817|0.068463|0.500000| |1.388202|1.526106|1.692853|1.878931|1.842021|2.016430|1.890550|1.655761|2.774216|2.788508|1.634599|1.505560|2.382254|16.606143|2.906913|4.653366|4.380335|4.367792|5.808879|8.868928|44.641656|17.546411|4.830038|3.323761|5.402755|3.878460|2.353824|2.183189|2.252318|0.037847|0.036276|0.038715|0.046955|0.057437|0.054613|0.038789|0.070034|0.070430|0.301925|0.500000| |1.357678|1.480741|1.648387|1.810543|1.748775|1.883228|1.751252|1.545467|2.582972|2.631233|1.554187|1.446059|2.209785|15.999964|2.828576|4.348541|4.127218|4.576558|6.895483|8.879865|36.311771|17.626706|6.732648|3.549894|6.023724|3.955581|2.428153|2.319045|2.320438|0.037365|0.035372|0.037846|0.046235|0.055597|0.050031|0.037252|0.064925|0.063744|0.302299|0.302294|0.500000| |1.486708|1.624461|1.833197|2.014658|1.910406|2.034147|1.856431|1.632377|2.699325|2.805623|1.680096|1.568285|2.405097|19.205658|3.566931|4.941767|4.608864|6.577995|8.887643|5.866808|29.248260|4.823271|17.588796|6.056475|12.248054|5.737864|3.552761|3.592291|3.340118|0.041684|0.038418|0.040913|0.051913|0.062794|0.052345|0.040107|0.069568|0.066885|0.117692|0.109812|0.148820|0.500000| |1.369723|1.493450|1.666607|1.829873|1.760840|1.891745|1.753149|1.546559|2.580380|2.638146|1.562181|1.454950|2.222872|16.994854|3.075272|4.465966|4.229498|5.456181|8.849264|7.054700|30.648351|6.787051|17.620678|4.508243|8.312258|4.629460|2.869799|2.784247|2.786417|0.038080|0.035633|0.037858|0.046855|0.056366|0.049967|0.037438|0.064243|0.063253|0.149679|0.149893|0.250527|0.301307|0.500000| |1.413690|1.553060|1.731888|1.920633|1.866998|2.031795|1.889270|1.653895|2.759856|2.798949|1.650396|1.523864|2.407199|19.209276|3.567541|4.942455|4.609708|6.578773|8.888255|5.867304|29.252720|4.823922|17.588944|6.056585|12.240984|5.738975|3.554142|3.338920|3.596951|0.039418|0.036824|0.038683|0.048274|0.059111|0.054238|0.039163|0.067980|0.068725|0.109739|0.117853|0.148764|0.304225|0.301321|0.500000| |2.249212|2.623067|3.011927|3.564207|3.518219|3.881132|3.395959|2.845476|4.505023|4.836971|2.945515|2.604702|4.600947|58.393013|7.601113|6.850811|4.183443|4.267854|3.251432|2.830612|21.636934|2.314978|2.934385|5.703400|9.005842|12.578170|17.707545|9.053579|9.055407|0.063760|0.057648|0.058462|0.080396|0.110231|0.093046|0.064601|0.115474|0.115824|0.060740|0.060760|0.061431|0.083554|0.069992|0.083587|0.500000| |1.864981|2.063367|2.354856|2.596662|2.430765|2.531582|2.261739|1.991413|3.236792|3.475085|2.118381|1.977794|2.923735|27.713224|4.668481|5.147532|3.769898|4.498691|3.689656|2.995908|20.451799|2.477200|3.697672|6.563893|14.119466|9.080477|8.756372|17.659080|6.736634|0.053717|0.047765|0.049762|0.066450|0.080895|0.062129|0.050014|0.080631|0.076337|0.064902|0.062763|0.068436|0.115955|0.085634|0.104895|0.175135|0.500000| |2.049129|2.277481|2.577191|2.825571|2.663709|2.730262|2.443412|2.175787|3.520896|3.831078|2.341961|2.191228|3.036106|30.062059|4.358175|4.670337|3.193560|3.500153|2.889953|2.475713|17.721011|2.090884|2.811604|4.659806|8.749576|7.576807|8.905767|17.550916|6.795806|0.059712|0.052540|0.053684|0.071908|0.086035|0.066198|0.055369|0.081408|0.077525|0.055393|0.054079|0.057085|0.084404|0.067576|0.079951|0.222065|0.300892|0.500000| |2.248877|2.532038|2.990895|3.338375|3.004815|3.048169|2.617833|2.284642|3.631321|4.055923|2.548066|2.378805|3.533894|35.182784|5.533194|5.843715|3.960261|4.301297|3.411074|2.909376|21.188892|2.396603|3.186279|5.719870|9.826202|9.588927|8.809021|17.555001|5.451435|0.065236|0.056566|0.059619|0.085168|0.107172|0.070026|0.058979|0.098821|0.087847|0.064167|0.060898|0.064552|0.097244|0.075619|0.086898|0.215359|0.300314|0.301690|0.500000| |1.795218|2.014342|2.211605|2.481128|2.496743|2.720488|2.559460|2.253660|3.731722|3.803797|2.225982|2.022109|3.041449|30.055928|4.358639|4.671772|3.195195|3.502043|2.891719|2.477163|17.730528|2.092121|2.813388|4.661078|8.747970|7.576969|8.906118|6.796425|17.551151|0.051108|0.047011|0.046957|0.059695|0.073703|0.072390|0.051848|0.077711|0.081996|0.054089|0.055454|0.057113|0.079965|0.067618|0.084497|0.222097|0.166926|0.202908|0.139877|0.500000| |1.663679|1.857697|2.060848|2.316523|2.299223|2.523688|2.355145|2.052084|3.402410|3.454305|2.029558|1.848166|2.928726|27.709318|4.669240|5.149695|3.772767|4.502864|3.693443|2.998586|20.467327|2.479338|3.701773|6.567428|14.111077|9.080857|8.756166|6.736223|17.658783|0.047074|0.043413|0.044159|0.056281|0.070200|0.067295|0.047319|0.076960|0.080703|0.062786|0.064995|0.068486|0.104964|0.085721|0.116147|0.175150|0.198329|0.166897|0.138488|0.300897|0.500000| |1.776551|2.022033|2.231717|2.572246|2.645295|3.026174|2.870415|2.440833|4.042553|4.003333|2.317532|2.055714|3.548231|35.172180|5.535069|5.848456|3.965247|4.306666|3.415516|2.913047|21.214947|2.399519|3.190169|5.722943|9.820524|9.589200|8.810088|5.451797|17.557370|0.049750|0.046550|0.046764|0.059558|0.077160|0.083869|0.052480|0.088855|0.099797|0.060951|0.064279|0.064614|0.086960|0.075709|0.097405|0.215454|0.138496|0.139882|0.122832|0.301717|0.300296|0.500000|
1972.753585 -10626.497205 3900.094212 -210.460992 -4964.110399 2989.644901 -1974.465498 2.000868 408A400000000001 4460662E73B70BD0 43E2BDEBF1F5C45B 4181022C40000004 C014000000000000 438150BC94A2E30A