Version2.0
2020-02-05T00:23:06Z
10.1021/jm300687e
Gaussian16
RevisionB.01
CFLINN
13-Sep-2019
#N HF/6-31G(d) OPT=(MaxStep=1) FREQ IOp(6/10=2,6/11=2,6/12=2)
DUDE CC1=C([C@H](n2c(c(cn2)C(=O)Nc3ccccc3)N1)c4ccccc4F)C(=O)Nc5ccc(cc5)Cl C20135072
RHF
6-31G(d)
(6D,7F)
CC1=C([C@H](n2c(c(cn2)C(=O)Nc3ccccc3)N1)c4ccccc4F)C(=O)Nc5ccc(cc5)Cl
C01[X(C27H21Cl1F1N5O2)]
165
C1
586
Clc1ccc(cc1)NC(=O)C1=C(C)Nc2n([C@@H]1c1ccccc1F)ncc2C(=O)Nc1ccccc1
Clc1ccc(cc1)NC(=O)C1=C(C)Nc2n([C@@H]1c1ccccc1F)ncc2C(=O)Nc1ccccc1
CC1=C([C@H](n2ncc(C(=O)Nc3ccccc3)c2N1)c4ccccc4F)C(=O)Nc5ccc(Cl)cc5
InChIKey=GRMAMFNDRWBFFM-XMMPIXPASA-N
InChI=1S/C27H21ClFN5O2/c1-16-23(27(36)33-19-13-11-17(28)12-14-19)24(20-9-5-6-10-22(20)29)34-25(31-16)21(15-30-34)26(35)32-18-7-3-2-4-8-18/h2-15,24,31H,1H3,(H,32,35)(H,33,36)/t24-/m1/s1
InChI=1/C27H21ClFN5O2/c1-16-23(27(36)33-19-13-11-17(28)12-14-19)24(20-9-5-6-10-22(20)29)34-25(31-16)21(15-30-34)26(35)32-18-7-3-2-4-8-18/h2-15,24,31H,1H3,(H,32,35)(H,33,36)/t24-/m1/s1/f/h32-33H
CC1=C([C@H](n2c(c(cn2)C(=O)Nc3ccccc3)N1)c4ccccc4F)C(=O)Nc5ccc(cc5)Cl
C01[X(C27H21Cl1F1N5O2)]
165
C01
586
Clc1ccc(cc1)NC(=O)C1=C(C)Nc2n([C@@H]1c1ccccc1F)ncc2C(=O)Nc1ccccc1
O=C([C@H]1CNN2[C@H]1NC(=C([C@H]2c1ccccc1F)C(=O)Nc1ccc(cc1)Cl)C)Nc1ccccc1
CC1=C([C@H](N2NC[C@@H]([C@@H]2N1)C(=O)Nc3ccccc3)c4ccccc4F)C(=O)Nc5ccc(Cl)cc5
InChIKey=CKRVGYIONNSFAC-FTBPSBKWSA-N
InChI=1S/C27H25ClFN5O2/c1-16-23(27(36)33-19-13-11-17(28)12-14-19)24(20-9-5-6-10-22(20)29)34-25(31-16)21(15-30-34)26(35)32-18-7-3-2-4-8-18/h2-14,21,24-25,30-31H,15H2,1H3,(H,32,35)(H,33,36)/t21-,24+,25+/m0/s1
InChI=1/C27H25ClFN5O2/c1-16-23(27(36)33-19-13-11-17(28)12-14-19)24(20-9-5-6-10-22(20)29)34-25(31-16)21(15-30-34)26(35)32-18-7-3-2-4-8-18/h2-14,21,24-25,30-31H,15H2,1H3,(H,32,35)(H,33,36)/t21-,24+,25+/m0/s1/f/h32-33H
3710.8773909928
-2015.5862245
1-A
28115.3861
130
456
586
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10.98134
2.8002 -0.7932 4.0130
4.9572
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-226.0571 -205.7139 -214.0246 3.8127 -10.6361 3.2671
|XX|YY|ZZ|XY|XZ|YZ|
-10.7919 9.5513 1.2406 3.8127 -10.6361 3.2671
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431.8345 21.3954 16.9032 4.7294 114.8037 -15.6502 -61.1217 1.2900 32.4088 -18.9892
|XXXX|YYYY|ZZZZ|XXXY|XXXZ|YYYZ|ZZZX|ZZZY|XXYY|XXZZ|YYZZ|XXYZ|YYXZ|ZZXY|
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|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|
10.6879 13.5188 17.4565 20.5242 23.0456 25.7453 46.6979 51.8867 54.5848 70.7388 75.9368 91.3707 116.9604 131.6625 137.2936 165.3420 172.5106 180.5317 183.3955 213.2298 237.2036 253.2330 256.8232 283.5918 295.2070 311.5883 337.0394 361.2020 380.2236 384.0405 388.9040 412.1873 454.1879 455.9687 459.3057 476.1031 490.3456 521.3011 533.7090 544.2562 552.1618 568.5359 572.0403 575.8554 594.6657 598.8473 606.1854 613.7609 650.7891 668.3574 676.0310 682.7833 694.4082 717.4180 728.8447 762.9579 770.4055 776.5831 784.7950 816.8795 849.7035 854.3317 860.0640 864.5580 865.7071 873.8669 897.1329 912.0685 924.6470 925.6926 933.6084 942.6029 959.1463 966.7894 974.9564 993.6790 1007.3633 1023.6261 1072.9636 1079.8756 1085.7217 1090.0074 1096.3557 1107.8952 1110.0107 1113.5632 1120.5904 1124.3810 1134.9817 1138.2956 1168.0220 1187.5172 1188.6114 1200.6609 1201.6472 1209.3346 1214.5653 1216.2140 1217.9569 1269.7673 1281.3802 1303.8995 1307.1808 1310.2113 1320.5003 1325.2044 1330.9503 1335.8236 1361.9544 1383.7931 1386.1914 1395.4853 1411.0962 1417.1942 1439.9014 1455.4339 1476.9605 1480.1686 1522.1451 1532.8572 1556.4101 1568.6215 1582.6851 1614.1464 1626.1633 1631.8556 1637.6761 1672.7119 1672.9433 1674.4388 1677.7695 1704.9213 1732.5919 1745.7185 1776.9860 1791.4676 1795.3993 1803.5118 1806.7566 1809.7656 1818.8157 1875.9270 1898.5678 1954.0415 3212.8875 3266.9334 3321.3198 3341.8370 3353.4094 3356.3505 3360.1193 3361.0315 3372.4478 3374.0927 3389.1146 3389.1689 3398.5438 3401.4817 3403.8545 3417.1361 3467.8514 3468.0095 3849.6403 3886.4818 3891.1109
4.8588 7.3466 4.6561 5.9513 6.1119 5.3192 7.1279 6.4375 7.3934 7.2684 5.6240 7.3380 3.0674 7.2572 6.9101 1.7370 4.7870 4.6829 5.4084 6.0120 5.0062 6.0442 6.2435 5.5982 5.7204 7.3798 4.9597 5.2044 5.4101 6.2821 6.4107 6.0552 8.2614 2.9907 3.0574 5.4827 5.4324 5.6580 3.2111 1.2835 3.9042 5.3866 2.8619 2.7890 2.6773 3.0025 1.2670 2.6421 3.6324 5.9058 5.4967 5.3812 6.9447 4.9372 5.8960 6.3494 2.1547 9.0063 3.5146 4.9748 1.8009 2.2433 1.8710 6.1645 5.7625 6.3845 6.2700 5.8968 4.1578 1.4219 5.1074 1.2645 1.4358 7.0120 1.9208 3.3597 1.3836 1.4178 1.3586 1.4456 4.8895 2.7547 1.3404 3.6935 1.3384 1.3123 2.4745 1.3107 2.2432 2.1334 1.5814 2.9612 3.1956 2.0700 2.4095 2.6906 2.5132 2.5144 2.4948 2.5077 2.3373 1.9070 1.2026 1.1951 2.0390 1.5736 2.2007 2.9932 3.9156 2.7305 2.8359 2.2389 2.2947 1.7891 2.1172 1.4443 1.7723 1.7862 2.3290 1.7889 2.6797 1.5193 2.1243 2.5719 2.2710 1.0686 1.0680 2.2893 2.5658 2.2683 3.2191 2.2080 2.4599 6.9173 4.1970 4.1224 6.1435 3.9799 5.4029 4.9562 6.2050 7.3278 6.9366 9.3296 1.0439 1.1012 1.0863 1.0894 1.0910 1.0974 1.0882 1.0888 1.0940 1.0914 1.0983 1.0959 1.0931 1.0950 1.0969 1.0974 1.0936 1.0933 1.0801 1.0783 1.0776
0.0003 0.0008 0.0008 0.0015 0.0019 0.0021 0.0092 0.0102 0.0130 0.0214 0.0191 0.0361 0.0247 0.0741 0.0767 0.0280 0.0839 0.0899 0.1072 0.1611 0.1660 0.2284 0.2426 0.2653 0.2937 0.4221 0.3319 0.4001 0.4608 0.5459 0.5713 0.6061 1.0041 0.3663 0.3800 0.7322 0.7696 0.9059 0.5389 0.2240 0.7013 1.0258 0.5518 0.5449 0.5578 0.6344 0.2743 0.5864 0.9064 1.5543 1.4801 1.4781 1.9730 1.4972 1.8453 2.1776 0.7535 3.2002 1.2754 1.9559 0.7661 0.9647 0.8154 2.7148 2.5445 2.8725 2.9733 2.8901 2.0944 0.7179 2.6229 0.6619 0.7782 3.8615 1.0757 1.9545 0.8273 0.8753 0.9215 0.9932 3.3959 1.9283 0.9493 2.6711 0.9716 0.9588 1.8308 0.9763 1.7025 1.6287 1.2711 2.4604 2.6600 1.7582 2.0499 2.3184 2.1843 2.1913 2.1805 2.3822 2.2611 1.9102 1.2107 1.2088 2.0949 1.6282 2.2968 3.1469 4.2793 3.0806 3.2106 2.5688 2.6921 2.1171 2.5863 1.8026 2.2779 2.3057 3.1793 2.4765 3.8247 2.2026 3.1352 3.9481 3.5384 1.6765 1.6876 3.7740 4.2309 3.7471 5.3389 3.7814 4.3506 12.4204 7.8082 7.7951 11.6677 7.6271 10.3915 9.5641 12.0939 15.1934 14.7316 20.9885 6.3486 6.9244 7.0603 7.1679 7.2286 7.2840 7.2388 7.2465 7.3307 7.3208 7.4329 7.4170 7.4388 7.4646 7.4881 7.5500 7.7489 7.7472 9.4308 9.5962 9.6129
0.0387 0.0135 0.3327 0.2049 0.3000 0.1421 0.5481 0.2974 5.2630 4.8270 3.0256 1.9449 1.2704 0.4471 2.2569 0.7059 2.3282 0.3751 2.7320 5.4045 4.3474 3.8435 8.2838 1.2457 2.5699 3.7540 2.9789 6.6115 1.8832 3.4385 13.8430 22.6938 11.1628 0.5760 0.3349 6.5438 12.5240 3.2945 13.8022 76.1750 4.7931 2.2735 0.7362 11.2833 35.1066 13.5034 90.3689 27.6634 19.7489 4.2711 2.5214 8.2333 0.7227 2.3972 16.7566 37.5497 18.4333 6.3482 0.1047 8.6026 28.1156 79.2147 44.9535 41.3907 33.6966 29.8376 57.5089 9.4517 10.9483 27.1362 67.5314 0.0025 57.2125 60.4678 9.3680 5.0633 2.9538 13.1531 0.1189 6.8967 2.5441 14.7006 0.1157 21.3002 1.0921 0.1414 16.4260 1.7873 3.0220 1.2992 4.9342 143.1685 0.4168 19.5399 8.9244 17.4955 27.9814 48.9744 23.0860 3.8506 18.0694 9.6301 11.4975 5.0465 15.6477 1.4056 5.9008 62.7599 74.0797 51.9844 11.8123 661.5111 84.6133 39.5380 290.7582 91.1182 5.8408 168.5735 24.1791 36.0648 124.3798 12.0111 75.9017 157.9862 18.1271 28.1253 14.5148 286.0865 45.0583 167.2599 79.5620 935.9095 602.6894 190.1598 862.8452 42.9721 17.6151 150.0856 9.5225 0.5101 18.3764 85.2375 282.7634 288.8400 21.1033 14.2153 0.7187 18.2322 19.3075 9.3011 4.6915 0.4507 35.9857 11.7482 33.0147 22.1054 4.3192 4.4896 9.0849 14.1451 3.5107 2.3474 210.7058 23.6587 24.2867
5.0982 4.4014 6.0190 3.4108 2.9956 3.2420 2.4485 2.0459 1.5406 1.9014 1.6793 0.4895 1.6979 1.2176 2.4300 1.1938 0.6301 4.1743 3.2794 0.8029 2.0327 2.2140 0.3501 2.5252 0.7595 0.7426 1.0502 2.0291 1.4673 2.0514 1.4093 0.6138 2.1501 0.1633 0.0751 1.9700 3.3647 1.9681 7.5631 0.9375 7.6817 1.9239 1.5341 1.2065 3.6778 0.8495 3.1619 3.5200 3.3851 3.2592 10.5054 0.7510 4.9378 1.3385 6.3724 7.4164 1.9576 1.6327 1.7286 1.4248 0.9599 2.3893 1.4574 8.8776 6.0080 4.3520 14.5863 33.7546 6.5006 3.0079 14.0503 2.9825 0.7577 4.2986 2.2432 5.4301 2.6610 2.0646 2.2451 0.6744 34.4709 22.4368 0.2729 2.6916 0.9874 0.0464 10.5413 1.1212 8.4826 15.8238 3.6469 3.0499 2.5701 6.3266 3.2126 5.0029 8.3990 5.2974 13.0678 1.4012 2.1495 15.3996 5.6172 16.1518 25.7063 2.1082 7.8895 14.7879 40.1925 16.6610 3.4320 30.1626 90.0624 4.1911 21.0671 7.8524 5.5572 18.9228 6.9949 8.8388 3.2455 65.2661 61.5140 36.6941 0.3351 13.9433 18.7687 7.9860 12.0890 28.2259 90.4669 27.9070 62.5764 29.2720 23.7097 6.8305 8.4816 6.5883 217.3038 94.8684 30.0175 168.0347 224.0160 109.2957 142.7093 92.1668 43.9997 42.9027 50.4069 71.4111 33.8493 87.1530 89.1911 58.8444 251.0435 125.4401 83.6522 104.7666 209.4797 97.9783 47.9554 49.1858 109.9036 42.8702 53.1994
0.7491 0.7457 0.7499 0.7437 0.7494 0.7497 0.6716 0.7347 0.7248 0.7434 0.7462 0.7128 0.7495 0.7399 0.3424 0.7461 0.4859 0.7140 0.4498 0.7456 0.7274 0.6538 0.7312 0.4099 0.1188 0.6398 0.6321 0.7335 0.5696 0.6198 0.2610 0.7076 0.7205 0.7484 0.7488 0.2587 0.3528 0.6908 0.2690 0.4725 0.2002 0.4106 0.7080 0.4901 0.5200 0.7390 0.6779 0.5579 0.7352 0.7241 0.7107 0.7483 0.6659 0.3446 0.3225 0.0386 0.7499 0.6430 0.7497 0.0836 0.5331 0.5258 0.6992 0.5765 0.7474 0.4124 0.1380 0.1092 0.1833 0.5159 0.1490 0.7500 0.7477 0.1402 0.4132 0.7480 0.7500 0.7496 0.7468 0.7473 0.1547 0.2127 0.7446 0.1323 0.7491 0.7194 0.1862 0.7494 0.0881 0.1188 0.5664 0.0923 0.7406 0.1648 0.2817 0.3927 0.7110 0.0900 0.5543 0.2235 0.7499 0.2073 0.4203 0.2250 0.2530 0.6894 0.2528 0.5195 0.2346 0.0561 0.5233 0.3556 0.2489 0.4441 0.4222 0.4026 0.6616 0.7480 0.4997 0.7436 0.4540 0.2417 0.2884 0.4060 0.7390 0.6801 0.6817 0.4695 0.4639 0.4153 0.5461 0.3825 0.4807 0.2802 0.6108 0.3833 0.7485 0.7289 0.4089 0.4904 0.5970 0.2486 0.3059 0.2147 0.0537 0.6433 0.1904 0.5365 0.4005 0.5607 0.6575 0.5763 0.7325 0.7363 0.1994 0.1361 0.3701 0.2190 0.1672 0.3020 0.1971 0.2071 0.2082 0.1548 0.1374
0.8565 0.8543 0.8571 0.8530 0.8568 0.8570 0.8035 0.8470 0.8404 0.8528 0.8547 0.8323 0.8568 0.8505 0.5101 0.8546 0.6540 0.8331 0.6205 0.8542 0.8422 0.7906 0.8448 0.5815 0.2124 0.7803 0.7746 0.8463 0.7258 0.7652 0.4140 0.8288 0.8376 0.8561 0.8563 0.4111 0.5216 0.8171 0.4240 0.6417 0.3336 0.5822 0.8290 0.6578 0.6842 0.8499 0.8080 0.7162 0.8474 0.8400 0.8309 0.8560 0.7994 0.5126 0.4877 0.0743 0.8571 0.7827 0.8569 0.1544 0.6955 0.6892 0.8230 0.7314 0.8555 0.5840 0.2426 0.1969 0.3098 0.6807 0.2593 0.8571 0.8557 0.2459 0.5847 0.8558 0.8571 0.8569 0.8551 0.8554 0.2680 0.3507 0.8536 0.2337 0.8565 0.8368 0.3139 0.8568 0.1619 0.2123 0.7232 0.1690 0.8510 0.2829 0.4395 0.5639 0.8311 0.1651 0.7132 0.3654 0.8571 0.3434 0.5918 0.3674 0.4039 0.8162 0.4036 0.6838 0.3800 0.1063 0.6871 0.5246 0.3986 0.6150 0.5937 0.5741 0.7964 0.8559 0.6664 0.8530 0.6245 0.3893 0.4477 0.5775 0.8499 0.8096 0.8107 0.6390 0.6338 0.5869 0.7065 0.5534 0.6493 0.4377 0.7584 0.5542 0.8562 0.8432 0.5805 0.6581 0.7477 0.3983 0.4685 0.3535 0.1019 0.7829 0.3199 0.6983 0.5719 0.7185 0.7934 0.7312 0.8456 0.8481 0.3324 0.2396 0.5403 0.3593 0.2865 0.4639 0.3292 0.3431 0.3446 0.2680 0.2417
298.150
1.00000
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57
6 6 6 6 1 7 6 6 6 7 6 8 7 6 6 6 6 6 6 7 6 6 6 6 6 6 9 6 8 7 6 6 6 6 6 6 17 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
12.00000 12.00000 12.00000 12.00000 1.00783 14.00307 12.00000 12.00000 12.00000 14.00307 12.00000 15.99491 14.00307 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 14.00307 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 18.99840 12.00000 15.99491 14.00307 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 34.96885 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783
8213.7030 46250.8349 51267.1247
0.99999 -0.00407 -0.00025 0.00407 0.99995 0.00924 0.00021 -0.00924 0.99996
1
0.01055 0.00187 0.00169
0.21972 0.03902 0.03520
15.38 19.45 25.12 29.53 33.16 37.04 67.19 74.65 78.54 101.78 109.26 131.46 168.28 189.43 197.53 237.89 248.20 259.74 263.87 306.79 341.28 364.35 369.51 408.03 424.74 448.31 484.92 519.69 547.06 552.55 559.55 593.05 653.48 656.04 660.84 685.01 705.50 750.04 767.89 783.06 794.44 818.00 823.04 828.53 855.59 861.61 872.17 883.07 936.34 961.62 972.66 982.37 999.10 1032.20 1048.65 1097.73 1108.44 1117.33 1129.15 1175.31 1222.53 1229.19 1237.44 1243.91 1245.56 1257.30 1290.77 1312.26 1330.36 1331.87 1343.25 1356.20 1380.00 1390.99 1402.74 1429.68 1449.37 1472.77 1543.76 1553.70 1562.11 1568.28 1577.41 1594.01 1597.06 1602.17 1612.28 1617.73 1632.99 1637.75 1680.52 1708.57 1710.15 1727.48 1728.90 1739.96 1747.49 1749.86 1752.37 1826.91 1843.62 1876.02 1880.74 1885.10 1899.91 1906.67 1914.94 1921.95 1959.55 1990.97 1994.42 2007.79 2030.25 2039.03 2071.70 2094.04 2125.02 2129.63 2190.03 2205.44 2239.33 2256.90 2277.13 2322.40 2339.69 2347.88 2356.25 2406.66 2406.99 2409.14 2413.94 2453.00 2492.81 2511.70 2556.69 2577.52 2583.18 2594.85 2599.52 2603.85 2616.87 2699.04 2731.62 2811.43 4622.63 4700.39 4778.64 4808.16 4824.81 4829.04 4834.46 4835.77 4852.20 4854.57 4876.18 4876.26 4889.75 4893.97 4897.39 4916.50 4989.46 4989.69 5538.77 5591.78 5598.44
0.470490
0.499300
0.500245
0.403782
-2015.115734
-2015.086924
-2015.085980
-2015.182443
3.235385D-04
MUNgauss
RevisionA2.0
retrievium
05-Feb-2020
DUDE CC1=C([C@H](n2c(c(cn2)C(=O)Nc3ccccc3)N1)c4ccccc4F)C(=O)Nc5ccc(cc5)Cl C20135072
RHF
6-31G(d)
(6D,10F)
C1
501.136781
|X|Y|Z|
60.576470 32.251985 152.989239
66.861138
31
|36.858105|
|12.644382|36.858105|
|7.481772|14.266041|36.858105|
|4.820607|7.566688|12.488645|36.858105|
|4.198392|5.936699|8.940898|17.665285|0.500000|
|4.515785|6.976636|7.883886|13.108945|0.257349|53.358707|
|5.183534|8.009907|6.922021|7.682848|0.166946|19.577208|36.858105|
|3.899261|5.129332|4.627193|5.284025|0.127395|11.845835|13.772388|36.858105|
|3.260259|4.247731|4.253966|5.455856|0.138154|12.338931|8.707159|13.399987|36.858105|
|3.434182|4.676042|5.141580|7.770844|0.196772|19.149399|8.578665|8.441386|14.749175|53.358707|
|3.591785|4.275294|3.679182|3.857925|0.095925|7.230809|7.624719|13.035184|7.162066|7.020065|36.858105|
|4.043466|4.551509|3.686332|3.606382|0.089213|6.309573|6.739762|8.201307|5.151937|5.701147|15.712357|73.516695|
|2.860506|3.291809|2.966298|3.177007|0.081488|5.676758|5.173369|7.964198|6.220324|6.018454|14.020229|14.932384|53.358707|
|2.502659|2.753232|2.480372|2.587857|0.067247|4.358671|3.824803|5.064850|4.273334|4.537606|7.609401|11.563687|18.402080|36.858105|
|2.535910|2.689067|2.371245|2.390675|0.061982|3.905867|3.465250|4.238364|3.485468|3.900463|6.238937|11.676571|10.487566|13.697516|36.858105|
|2.175178|2.262398|2.025999|2.036467|0.053372|3.233505|2.767450|3.248952|2.814862|3.248942|4.297152|7.974098|6.976005|7.948737|13.742413|36.858105|
|1.918981|2.013915|1.841728|1.880985|0.049745|2.970335|2.471945|2.912555|2.638839|3.054071|3.657784|6.407339|6.177392|6.826222|7.881942|13.768002|36.858105|
|1.905936|2.042004|1.892675|1.973713|0.052372|3.157552|2.595210|3.146609|2.937377|3.334211|3.888841|6.398667|7.072508|7.903253|6.857899|7.989459|13.752922|36.858105|
|2.132585|2.337304|2.163455|2.290115|0.060416|3.773512|3.142439|4.019339|3.730158|4.052327|5.154574|7.891184|10.873332|13.678837|7.930860|6.924483|7.938159|13.789060|36.858105|
|7.920949|13.742967|8.065729|6.631105|0.145438|11.142441|14.036085|7.617077|5.389108|7.415049|6.170964|11.901611|5.854751|3.436152|3.318388|2.685925|2.351973|2.394988|2.808833|53.358707|
|3.884509|5.345708|7.522106|12.497222|0.248506|10.557918|5.442217|4.262858|4.586982|8.518683|3.276565|5.441470|3.826343|2.338841|2.160271|1.869529|1.747067|1.838411|2.112178|6.610915|36.858105|
|3.808679|5.011913|6.121555|7.478303|0.155211|8.411843|5.066775|4.089746|4.192107|7.008064|3.266684|5.509958|3.818061|2.357508|2.196403|1.903529|1.772319|1.854689|2.121700|6.447636|13.685064|36.858105|
|3.062312|3.718476|4.323937|4.983296|0.116345|5.935619|3.757064|3.263969|3.406610|5.446189|2.732439|4.623115|3.313939|2.098747|1.962317|1.731459|1.630925|1.707452|1.927198|4.841837|7.875283|13.792155|36.858105|
|2.649332|3.152102|3.735789|4.410611|0.111004|5.150524|3.191055|2.840349|3.062602|4.958448|2.392944|4.021118|2.964105|1.895337|1.765918|1.575082|1.499661|1.577030|1.768509|4.065746|6.816106|7.954668|13.718286|36.858105|
|2.667865|3.221184|3.983119|4.988419|0.133377|5.527874|3.269999|2.889864|3.200230|5.403589|2.391953|3.986050|2.962845|1.882687|1.744256|1.553490|1.482416|1.565097|1.760654|4.094757|7.859680|6.891236|7.939882|13.797042|36.858105|
|3.126985|3.970669|5.270963|7.527430|0.204585|7.390113|4.044743|3.428604|3.836178|6.940590|2.734435|4.526919|3.315312|2.067497|1.906816|1.677539|1.589117|1.679199|1.909073|4.955281|13.798559|8.048763|6.941290|8.007882|13.788727|36.858105|
|2.936140|3.657053|4.822530|6.742991|0.226584|6.784125|3.727789|3.221538|3.664005|6.634546|2.587451|4.272104|3.171486|1.987587|1.830348|1.617840|1.539746|1.630414|1.848537|4.552333|8.142393|5.311101|4.677460|5.322899|8.205435|14.339678|97.533100|
|6.163305|7.594684|12.696095|7.577766|0.197368|6.902352|4.489778|3.404374|3.258002|5.263673|2.859367|5.131062|3.278769|2.079234|2.009253|1.757337|1.613185|1.649638|1.851442|6.873160|6.150909|5.059369|3.959048|3.624455|3.958269|5.061763|10.917740|36.858105|
|4.723815|5.543845|8.109472|6.573870|0.204327|6.173724|3.904328|3.097294|3.067021|4.999449|2.609875|4.613726|3.058018|1.950608|1.873879|1.652343|1.530905|1.572663|1.759045|5.631095|5.411637|4.249536|3.494801|3.384696|3.880613|4.996520|11.994138|15.895230|73.516695|
|6.028485|6.251084|7.867266|5.332456|0.134326|5.455189|3.754541|2.952420|2.786427|4.338317|2.574051|4.709667|2.982137|1.926421|1.888266|1.668179|1.528853|1.549736|1.720149|5.930991|5.035069|4.720558|3.912490|3.523910|3.642476|4.273425|8.818808|13.973591|14.965388|53.358707|
|4.442998|4.315880|5.027079|3.940121|0.104688|4.250176|2.941077|2.425109|2.324204|3.563584|2.163976|3.955864|2.566937|1.687636|1.662800|1.491178|1.376500|1.391169|1.526345|4.502734|3.908549|3.730348|3.345224|3.154415|3.256328|3.609346|7.668669|7.621630|11.606863|18.418762|36.858105|
|3.920243|3.670455|3.994366|3.256025|0.084986|3.686929|2.613069|2.201652|2.096322|3.149271|2.005154|3.695956|2.398342|1.595759|1.585406|1.432765|1.322554|1.329188|1.447309|4.010623|3.338084|3.385316|3.167351|2.954059|2.920854|3.091926|6.430653|5.154180|7.916487|10.865617|13.686206|36.858105|
|3.111580|2.914809|3.130796|2.674476|0.071409|3.102440|2.200870|1.900804|1.827081|2.720271|1.751651|3.218699|2.127270|1.431032|1.424900|1.301341|1.208549|1.212818|1.310079|3.311713|2.754026|2.777837|2.682841|2.578567|2.558895|2.641774|5.610905|3.889451|6.413743|7.067960|7.894004|13.797316|36.858105|
|2.803575|2.664970|2.906795|2.535860|0.069569|2.934106|2.058757|1.791935|1.741950|2.603485|1.647337|3.005398|2.014648|1.356932|1.346161|1.233389|1.151119|1.158307|1.249414|3.049939|2.583672|2.525635|2.438935|2.409321|2.458909|2.546594|5.575823|3.673954|6.443669|6.200868|6.862540|7.986813|13.784514|36.858105|
|2.972672|2.878474|3.233808|2.816416|0.079052|3.189766|2.204621|1.903602|1.863538|2.818956|1.729767|3.136182|2.108917|1.410493|1.391083|1.268817|1.185033|1.197453|1.297819|3.245103|2.817856|2.655773|2.514548|2.511807|2.646092|2.808930|6.316303|4.307536|8.001026|6.975129|7.935965|6.915565|7.953688|13.800026|36.858105|
|3.650530|3.597318|4.213239|3.522248|0.098837|3.836312|2.619405|2.206225|2.152259|3.305825|1.972692|3.572644|2.372428|1.567611|1.539345|1.389815|1.292049|1.309207|1.431027|3.893451|3.452924|3.170114|2.899117|2.854072|3.052006|3.369438|7.562925|6.260555|11.714181|10.497802|13.699690|7.940829|6.852227|7.932018|13.751269|36.858105|
|2.252549|2.145336|2.296805|2.065317|0.057055|2.453861|1.732242|1.539394|1.504130|2.222442|1.432084|2.608122|1.774545|1.207807|1.201175|1.111381|1.043125|1.047850|1.121436|2.533533|2.110495|2.076771|2.044030|2.045105|2.077255|2.110353|4.664185|2.757439|4.914154|4.375894|4.214504|4.771267|7.028710|10.922111|7.024249|4.755110|448.794386|
|17.556770|8.961582|5.859823|4.205775|0.105899|5.669008|4.939964|3.890387|3.197619|4.453280|3.727379|7.683795|4.033288|2.619591|2.694872|2.305591|2.013509|1.983181|2.212508|9.925098|3.358660|3.245496|2.666121|2.349570|2.385522|2.779654|6.014374|4.930121|7.318576|6.315168|3.684254|3.289013|2.723955|2.511937|2.671460|3.196584|16.612659|0.500000|
|17.537080|8.901964|5.914512|4.186403|0.099993|5.493176|4.709673|3.687145|3.060042|4.300198|3.512892|7.193716|3.832507|2.498547|2.569272|2.212490|1.939478|1.910050|2.123407|9.541866|3.607198|3.744475|3.072529|2.609105|2.555854|2.913953|6.026997|5.010797|6.958719|7.263150|4.119411|3.885602|3.093146|2.714599|2.787103|3.322949|17.699426|0.302099|0.500000|
|17.678982|8.802759|6.975079|4.484223|0.112746|5.378994|4.226588|3.291044|2.877936|4.208160|3.015949|5.870153|3.380882|2.201216|2.222578|1.941248|1.734407|1.725394|1.912134|7.759327|3.722432|3.587702|2.953480|2.610186|2.654410|3.092390|6.619836|7.045680|9.502395|10.162075|5.503471|4.680694|3.624859|3.262105|3.500871|4.417657|20.455718|0.302021|0.300570|0.500000|
|2.760986|3.429254|3.450398|4.288838|0.113290|8.312671|5.878514|8.461104|17.763973|12.708849|6.101819|7.892140|8.503094|4.400822|3.451128|2.835518|2.735318|3.143083|4.063289|5.671252|3.833520|3.563152|3.045628|2.809607|2.931777|3.392677|7.416322|2.779264|4.738382|3.295592|2.067876|1.883817|1.664750|1.596330|1.701464|1.937879|11.200104|0.075917|0.072811|0.068864|0.500000|
|2.657047|3.104357|2.893624|3.211933|0.083354|5.790403|4.943870|7.708384|7.219694|6.597606|9.502199|10.871281|26.094796|9.372085|5.747926|4.301054|4.089498|4.950159|7.715931|5.361181|2.878448|2.839841|2.482723|2.246523|2.261840|2.528188|5.469569|2.365697|3.966417|2.907052|1.845380|1.717687|1.528270|1.454408|1.527616|1.717018|10.303878|0.075448|0.072045|0.065056|0.228287|0.500000|
|2.876080|3.005125|2.578409|2.539255|0.065206|4.137838|3.788166|4.485708|3.515781|3.995409|6.811007|15.134865|9.510833|8.914781|17.835561|8.913407|5.631530|4.953331|5.647962|5.138973|2.267559|2.313906|2.044476|1.822727|1.796795|1.976258|4.250110|2.165719|3.552688|2.779822|1.785617|1.703147|1.521314|1.429985|1.476141|1.640554|10.186906|0.086009|0.081639|0.068891|0.093202|0.143174|0.500000|
|2.137526|2.176654|1.938246|1.918355|0.050298|2.994814|2.556364|2.903156|2.511566|2.962915|3.733420|7.233388|5.650164|5.661613|8.972292|17.711476|8.928691|5.666465|4.978250|3.466057|1.764480|1.802169|1.644983|1.496573|1.472744|1.585450|3.439924|1.697334|2.832786|2.212619|1.461203|1.412035|1.286619|1.217721|1.247666|1.361101|8.834896|0.063282|0.060863|0.053167|0.069347|0.098309|0.216435|0.500000|
|1.751505|1.819486|1.673341|1.701530|0.045204|2.645438|2.173059|2.502298|2.298437|2.711765|3.038680|5.386631|4.918225|4.928229|5.620158|8.898679|17.724478|8.895644|5.643098|2.843350|1.591453|1.615650|1.499503|1.386570|1.369590|1.458874|3.187682|1.483257|2.511246|1.924606|1.283395|1.238503|1.138467|1.086297|1.115208|1.208847|7.947867|0.050984|0.049271|0.044351|0.066074|0.092637|0.123952|0.214620|0.500000|
|1.733554|1.856470|1.742644|1.828192|0.048855|2.890973|2.326535|2.777566|2.673792|3.083025|3.279733|5.375915|5.748148|5.637683|4.944057|5.661859|8.902370|17.714906|8.958307|2.916799|1.719417|1.730762|1.609508|1.500316|1.491302|1.588829|3.484763|1.534503|2.617275|1.964893|1.304627|1.248098|1.144712|1.097007|1.133719|1.234058|8.005099|0.049847|0.048157|0.043996|0.080566|0.117337|0.107528|0.124250|0.213899|0.500000|
|2.063265|2.294825|2.163692|2.340307|0.062148|3.876554|3.140669|4.062884|4.011913|4.307435|4.841121|7.101086|10.047778|8.892171|5.638303|4.976313|5.649342|8.943594|17.687325|3.722200|2.174056|2.168082|1.977364|1.829366|1.830694|1.982690|4.335356|1.854040|3.152224|2.329622|1.519622|1.435281|1.300267|1.244211|1.296554|1.430515|8.966994|0.058919|0.056664|0.051724|0.128009|0.237725|0.124060|0.107912|0.124184|0.216847|0.500000|
|7.467327|9.099420|5.826717|4.930092|0.115337|8.115990|9.505850|7.009184|4.771611|6.141197|6.817547|15.464764|6.256175|3.754524|3.764122|2.991643|2.551995|2.551688|2.979208|26.001877|3.890099|3.898339|3.084874|2.620748|2.611818|3.062937|6.411875|4.148848|6.228119|5.109520|2.968561|2.710581|2.274606|2.093439|2.202417|2.590506|14.146985|0.215720|0.198418|0.146798|0.106951|0.111711|0.124121|0.079412|0.062628|0.062603|0.078685|0.500000|
|4.359038|5.843146|6.450136|6.959597|0.140515|8.753465|5.860420|4.573616|4.369576|6.886486|3.688654|6.342284|4.186528|2.569904|2.415919|2.069969|1.902204|1.975847|2.268861|7.812933|8.932947|17.705617|8.949147|5.655310|4.960566|5.697083|9.602063|4.939856|7.102345|6.446932|3.657810|3.386098|2.749721|2.460957|2.555907|3.041410|16.263013|0.101396|0.122971|0.109567|0.101142|0.084742|0.071665|0.054521|0.047929|0.050724|0.063626|0.129793|0.500000|
|2.892229|3.390342|3.737852|4.070620|0.096223|5.106485|3.414697|3.037801|3.095381|4.724925|2.626073|4.495588|3.210975|2.061990|1.944243|1.725622|1.624678|1.692216|1.896404|4.498269|5.621053|8.929881|17.726165|8.895093|5.646487|4.988083|8.327053|3.433941|5.370632|4.788096|3.075783|3.026258|2.592972|2.324353|2.344298|2.648891|15.842837|0.070273|0.082821|0.077093|0.077936|0.066318|0.056286|0.045712|0.041613|0.044322|0.053744|0.081704|0.215931|0.500000|
|2.335938|2.697983|3.102717|3.531742|0.090921|4.266318|2.726822|2.484702|2.664612|4.180721|2.144141|3.620357|2.696212|1.749541|1.636977|1.474932|1.412420|1.483247|1.648280|3.509955|4.922891|5.651406|8.894896|17.723714|8.948721|5.678563|9.639190|3.061772|5.150386|4.146067|2.823881|2.715732|2.432833|2.280359|2.341425|2.589589|15.863815|0.058148|0.064522|0.064246|0.069285|0.056763|0.046717|0.039039|0.036475|0.039416|0.047365|0.064117|0.124261|0.214138|0.500000|
|2.363639|2.783223|3.372483|4.094328|0.114928|4.674885|2.823273|2.550415|2.837768|4.691060|2.146981|3.581368|2.699131|1.734408|1.608679|1.445393|1.388525|1.467353|1.639140|3.551863|5.635310|4.964153|5.627045|8.852358|17.743587|8.977158|16.904826|3.446267|6.235548|4.344406|2.961688|2.672110|2.404542|2.358187|2.547554|2.872278|16.290135|0.059546|0.062789|0.065923|0.073811|0.057438|0.045784|0.038118|0.035805|0.039082|0.047482|0.063948|0.107699|0.123645|0.213166|0.500000|
|6.624844|6.761710|7.679206|5.203279|0.123925|5.559534|3.950699|3.084788|2.854918|4.378464|2.709862|5.012640|3.112196|2.009727|1.979355|1.742185|1.588023|1.604506|1.782645|6.440379|5.076482|5.189907|4.247659|3.636183|3.590736|4.119532|8.156548|9.512017|10.929918|26.087524|9.339446|7.664345|4.929877|4.091710|4.290406|5.741209|24.008404|0.134639|0.176293|0.213162|0.068597|0.061482|0.059830|0.047225|0.040725|0.041367|0.049055|0.113460|0.153075|0.108637|0.087293|0.085991|0.500000|
|4.156680|3.842937|4.034625|3.268617|0.082990|3.773074|2.721294|2.288736|2.152667|3.203832|2.098153|3.897772|2.497215|1.662737|1.659034|1.496126|1.375036|1.377846|1.500802|4.238212|3.385787|3.591033|3.363677|3.029108|2.901368|3.048855|6.185055|4.830056|7.114847|10.022503|8.890231|17.697565|8.971636|5.675442|4.972541|5.641465|31.638449|0.095024|0.120225|0.133712|0.053576|0.049425|0.049729|0.041024|0.035725|0.035834|0.041194|0.080039|0.102754|0.091441|0.077396|0.072660|0.235285|0.500000|
|2.822208|2.629213|2.762731|2.397272|0.063627|2.841063|2.036098|1.779965|1.707016|2.515012|1.657837|3.055325|2.025267|1.372277|1.372254|1.260000|1.171224|1.171747|1.259541|3.056622|2.486782|2.560385|2.516052|2.408438|2.346803|2.384034|5.030301|3.276595|5.385278|5.737132|5.627974|8.928575|17.747748|8.920081|5.654276|4.943567|53.630008|0.069361|0.079769|0.089153|0.043454|0.040356|0.040659|0.034717|0.030741|0.030759|0.034656|0.058994|0.071036|0.068919|0.064075|0.061460|0.116673|0.216475|0.500000|
|2.641904|2.580583|2.888891|2.583755|0.073892|2.961073|2.040281|1.783191|1.759895|2.656296|1.624518|2.931450|1.996539|1.340032|1.319313|1.208413|1.133562|1.147059|1.239923|2.963334|2.570136|2.394811|2.280612|2.312953|2.468417|2.610839|6.013880|3.737771|7.239190|5.644701|5.650704|4.976297|5.658130|8.943031|17.745799|8.943713|53.695546|0.067355|0.068497|0.084933|0.044967|0.040312|0.038714|0.032996|0.029700|0.030264|0.034483|0.056138|0.063713|0.059004|0.060336|0.067200|0.098086|0.107894|0.124365|0.500000|
|3.630211|3.690975|4.456623|3.795933|0.110935|4.068490|2.730348|2.295217|2.261970|3.513290|2.031250|3.648201|2.443581|1.606013|1.567424|1.411465|1.314927|1.338041|1.467810|3.996309|3.605609|3.170929|2.854085|2.845480|3.142614|3.574668|8.380245|6.835553|15.138202|9.508317|8.906315|5.649641|4.950226|5.657995|8.942349|17.832914|31.581700|0.089917|0.089222|0.120291|0.056502|0.049343|0.046272|0.038252|0.034112|0.035055|0.040903|0.073249|0.083599|0.071340|0.071058|0.082784|0.143063|0.124016|0.107517|0.216193|0.500000|
2013.367526
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4650.370516
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3710.877658
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2.001102
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