Version2.4 2021-04-30T12:48:07Z 10.1021/jm300687e Gaussian16 RevisionB.01 SBUNGAY 09-Jan-2019 #N HF/6-31G(d) OPT=(MaxStep=1) FREQ IOp(6/10=2,6/11=2,6/12=2) DUDE C[C@H](c1ccc(cc1)Cl)N(C)C(=O)Nc2nncs2 C43129299 RHF 6-31G(d) (6D,7F) C[C@H](c1ccc(cc1)Cl)N(C)C(=O)Nc2nncs2 C01[X(C12H13Cl1N4O1S1)] 90 C1 319 Clc1ccc(cc1)[C@H](N(C(=O)Nc1nncs1)C)C Clc1ccc(cc1)[C@H](N(C(=O)Nc1nncs1)C)C C[C@@H](N(C)C(=O)Nc1scnn1)c2ccc(Cl)cc2 InChIKey=CRXYDQWZTXMYCU-MRVPVSSYSA-N InChI=1S/C12H13ClN4OS/c1-8(9-3-5-10(13)6-4-9)17(2)12(18)15-11-16-14-7-19-11/h3-8H,1-2H3,(H,15,16,18)/t8-/m1/s1 InChI=1/C12H13ClN4OS/c1-8(9-3-5-10(13)6-4-9)17(2)12(18)15-11-16-14-7-19-11/h3-8H,1-2H3,(H,15,16,18)/t8-/m1/s1/f/h15H C[C@H](c1ccc(cc1)Cl)N(C)C(=O)Nc2nncs2 C01[X(C12H13Cl1N4O1S1)] 90 C01 319 Clc1ccc(cc1)[C@H](N(C(=O)Nc1nncs1)C)C O=C(N([C@@H]([C]1[CH][CH][C]([CH][CH]1)Cl)C)C)N[C]1=[N][N]=CS1 C[C@H]([C]1[CH][CH][C](Cl)[CH][CH]1)N(C)C(=O)Nc2scnn2 InChIKey=CRXYDQWZTXMYCU-MRVPVSSYSA-N InChI=1S/C12H13ClN4OS/c1-8(9-3-5-10(13)6-4-9)17(2)12(18)15-11-16-14-7-19-11/h3-8H,1-2H3,(H,15,16,18)/t8-/m1/s1 InChI=1/C12H13ClN4OS/c1-8(9-3-5-10(13)6-4-9)17(2)12(18)15-11-16-14-7-19-11/h3-8H,1-2H3,(H,15,16,18)/t8-/m1/s1/f/h15H 1603.7148104400 -1611.6258673 1-A 8961.9001 77 242 319 |A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A| -104.83055 -91.99278 -20.54067 -15.62954 -15.61018 -15.60157 -15.58836 -11.40439 -11.35819 -11.30834 -11.29919 -11.28992 -11.28674 -11.25831 -11.25591 -11.25477 -11.25421 -11.25059 -11.23579 -10.56394 -9.00368 -8.03334 -8.03000 -8.02997 -6.68578 -6.68494 -6.68306 -1.43457 -1.37623 -1.29000 -1.26400 -1.19958 -1.13446 -1.11403 -1.07134 -1.05727 -1.04101 -0.99337 -0.98480 -0.91074 -0.86014 -0.85166 -0.82611 -0.80351 -0.78112 -0.75005 -0.71871 -0.70871 -0.67566 -0.67452 -0.66205 -0.65053 -0.62558 -0.61940 -0.61474 -0.60521 -0.60142 -0.58467 -0.58011 -0.57697 -0.56196 -0.55091 -0.54956 -0.53423 -0.51240 -0.50641 -0.48454 -0.47307 -0.46282 -0.45725 -0.44990 -0.42215 -0.40470 -0.39583 -0.35739 -0.35335 -0.33664 |A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A|A| 0.11716 0.12216 0.12936 0.17536 0.19194 0.19879 0.20458 0.24136 0.24697 0.25577 0.26637 0.27462 0.28327 0.28765 0.29161 0.29828 0.30156 0.31652 0.31699 0.32243 0.33498 0.33989 0.35563 0.36717 0.38177 0.40147 0.40514 0.41638 0.44520 0.45277 0.46192 0.47297 0.49602 0.50545 0.51784 0.52422 0.54490 0.59000 0.59503 0.60309 0.61450 0.61805 0.62532 0.63311 0.64044 0.68350 0.69037 0.70469 0.71826 0.73862 0.75388 0.76915 0.77710 0.78052 0.78948 0.79162 0.80258 0.80686 0.80978 0.81538 0.82226 0.83447 0.85260 0.87432 0.88327 0.89396 0.90730 0.91245 0.92201 0.93447 0.94795 0.95445 0.96448 0.97518 0.98983 0.99583 1.00618 1.00858 1.01333 1.02743 1.03797 1.04509 1.04887 1.07037 1.08081 1.09095 1.09652 1.09979 1.10957 1.11329 1.12719 1.13679 1.13865 1.14656 1.15145 1.15619 1.16704 1.16742 1.17618 1.18713 1.19501 1.19837 1.20102 1.21731 1.22504 1.22941 1.24383 1.25612 1.26689 1.28115 1.29208 1.29750 1.31346 1.32231 1.35949 1.36511 1.37164 1.39355 1.39872 1.41487 1.42829 1.47403 1.48826 1.49539 1.51280 1.55440 1.57761 1.58545 1.60055 1.61932 1.62582 1.63548 1.65838 1.66473 1.69259 1.69862 1.71704 1.72536 1.73410 1.75965 1.77261 1.77413 1.77814 1.83404 1.84780 1.89064 1.90055 1.92890 1.93977 1.96987 2.00851 2.03270 2.07582 2.08762 2.09994 2.10990 2.13349 2.14475 2.16120 2.19316 2.22050 2.22615 2.23818 2.25620 2.26941 2.30004 2.30551 2.31322 2.32559 2.35009 2.37021 2.39278 2.40557 2.41860 2.43360 2.45600 2.46005 2.46939 2.47399 2.48721 2.51841 2.52975 2.57402 2.57940 2.60461 2.61842 2.62190 2.62413 2.65265 2.65659 2.67993 2.68647 2.69644 2.71634 2.76770 2.78453 2.80916 2.82269 2.88608 2.90101 2.91526 2.93652 2.94418 2.95229 2.97614 2.98320 3.00554 3.04866 3.05934 3.09017 3.12660 3.14277 3.14781 3.17132 3.18768 3.23512 3.36215 3.40268 3.45390 3.47256 3.62786 3.66100 3.78069 4.14176 4.33900 4.45281 4.48249 4.51211 4.52785 4.56281 4.58764 4.61148 4.66743 4.69776 4.70344 4.74179 4.75404 4.78206 4.80456 4.95017 5.05451 5.15298
12.34843
2.1193 2.7950 -0.0245 3.5077 |XX|YY|ZZ|XY|XZ|YZ| -148.3315 -117.1654 -130.0630 9.1327 -13.7101 -6.8387
|XX|YY|ZZ|XY|XZ|YZ| -16.4782 14.6879 1.7903 9.1327 -13.7101 -6.8387
|XXX|YYY|ZZZ|XYY|XXY|XXZ|XZZ|YZZ|YYZ|XYZ| 3.4917 2.5922 -2.5569 -1.0428 24.2388 98.5155 16.0550 7.4579 5.5412 18.4923
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0.0676 0.0591 0.0708 0.2626 0.1236 0.2523 0.0731 0.2590 0.2997 0.3613 1.0190 0.3730 0.6512 0.5942 0.2218 0.6109 0.8036 1.2282 2.1911 1.9922 3.0548 1.8073 1.1555 2.5674 1.7063 1.8675 4.0029 2.0289 0.6428 0.9614 1.0642 0.8238 2.7920 1.5501 1.0075 2.3719 1.0370 1.6753 1.6790 2.1747 1.7568 2.3986 2.2433 1.1821 2.0656 2.2539 1.1799 2.9684 5.1062 1.7915 1.6563 2.5128 8.4753 1.9197 2.1617 2.3932 2.4763 1.9131 1.6776 1.7159 1.7358 3.4675 2.6378 2.5886 15.4683 6.3839 11.3729 10.2951 20.3171 6.3187 6.3218 6.9512 6.9808 7.0403 7.1296 7.2284 7.3118 7.3568 7.4698 7.4817 7.6397 9.6447 0.1686 0.4346 0.1539 2.2476 7.0677 6.2351 3.2985 0.3308 0.1869 0.4040 1.7631 25.8176 0.9736 2.7167 0.6074 0.8321 2.1075 0.4447 2.3047 1.6511 12.0737 3.4130 69.2733 13.7046 11.5176 35.6898 9.6745 0.2565 14.5998 3.4619 14.7654 15.1437 12.1496 6.2229 37.7436 24.1987 14.6255 36.7333 1.1733 19.7708 3.7012 9.7554 2.2494 29.9296 1.1116 16.9024 11.9707 35.2613 10.6906 46.1515 56.3760 5.4765 120.3909 68.8488 0.0451 8.5372 25.9377 22.8962 2.9267 404.9994 171.1058 14.8846 73.2060 14.9761 25.8637 2.3134 6.9822 3.4881 13.9135 100.8818 66.8921 201.0693 3.5146 738.7078 9.6093 10.9024 461.1627 37.3969 22.0795 29.7211 29.7051 35.5974 6.9310 14.2336 4.3520 6.9689 7.3918 4.4499 1.9671 68.5919 2.9740 5.5668 6.4578 0.7512 0.4287 0.6516 0.2284 0.2401 0.1822 0.3199 0.8745 0.6959 0.9979 2.6323 0.2092 1.0912 1.9637 1.1004 0.7977 0.2758 4.2750 1.1164 0.9940 1.2768 0.6409 0.3105 3.6613 7.3032 1.8370 9.0875 5.6219 3.8295 3.7650 3.6200 0.2443 26.7994 1.8219 1.1784 2.7522 1.4750 6.5865 4.7227 0.8294 0.3401 0.1040 3.2096 10.8052 2.8860 3.0435 1.0620 13.6202 3.4777 2.5671 5.1738 3.6839 3.9591 11.5894 9.9866 1.0499 5.3679 2.9308 3.7639 21.4595 5.1380 1.7145 8.0986 23.3625 14.9129 6.7164 30.3262 8.7702 9.9571 8.9640 56.5310 6.2088 46.9986 33.4519 69.6274 139.0613 46.6926 56.2572 89.8259 44.2713 50.3732 53.7213 45.7860 41.4579 175.6347 158.6428 47.6488 0.7427 0.7477 0.7493 0.7272 0.7260 0.7317 0.6409 0.3004 0.4928 0.2942 0.0677 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298.150 1.00000 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 6 6 1 6 6 6 6 6 6 17 7 6 6 8 7 6 7 7 6 16 1 1 1 1 1 1 1 1 1 1 1 1 12.00000 12.00000 1.00783 12.00000 12.00000 12.00000 12.00000 12.00000 12.00000 34.96885 14.00307 12.00000 12.00000 15.99491 14.00307 12.00000 14.00307 14.00307 12.00000 31.97207 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783 1.00783
2472.2550 15037.5175 16070.1763 0.99995 0.00982 0.00062 -0.00981 0.99976 -0.01940 -0.00081 0.01939 0.99981 1 0.03503 0.00576 0.00539 0.73000 0.12002 0.11230 17.30 37.94 56.15 97.93 105.08 145.03 158.11 215.62 272.79 289.03 336.88 371.95 407.63 447.42 448.66 475.70 519.86 521.97 570.70 659.21 684.95 737.28 770.42 806.19 868.35 908.61 961.49 999.37 1003.86 1029.27 1074.05 1104.00 1171.72 1200.28 1220.57 1247.23 1358.02 1361.41 1365.10 1374.41 1425.59 1535.87 1567.23 1597.35 1600.61 1620.85 1686.59 1695.90 1718.43 1733.72 1746.00 1800.42 1830.81 1862.60 1887.02 1926.26 1985.10 2015.01 2086.96 2101.91 2116.52 2161.28 2231.49 2245.06 2272.97 2329.88 2361.80 2371.50 2383.98 2389.46 2408.89 2410.63 2473.58 2531.68 2547.23 2602.23 2746.21 4614.36 4627.84 4704.15 4716.57 4733.59 4801.62 4811.19 4852.63 4871.06 4894.72 4897.65 4947.22 5607.16 0.263621 0.280432 0.281376 0.215394 -1611.362246 -1611.345435 -1611.344491 -1611.410473 2.213047D-04
MUNgauss RevisionA2.1 retrievium 30-Apr-2021 DUDE C[C@H](c1ccc(cc1)Cl)N(C)C(=O)Nc2nncs2 C43129299 RHF 6-31G(d) (6D,10F) C1 296.049861 |X|Y|Z| 32.701540 22.327670 85.988207
39.745091 15 6 7 16 10 4 1
|36.858105| |12.462514|36.858105| |9.000525|17.691926|0.500000| |7.380353|12.478784|0.250662|36.858105| |4.949637|7.596988|0.197462|13.658398|36.858105| |3.815130|5.019943|0.132047|7.874387|13.808235|36.858105| |3.673993|4.422100|0.112178|6.846404|7.984599|13.739809|36.858105| |4.377318|4.958605|0.119227|7.879353|6.893659|7.930077|13.830917|36.858105| |6.422237|7.418352|0.161483|13.749617|7.987570|6.884473|7.975400|13.707075|36.858105| |2.765528|3.148329|0.082354|4.209370|4.774081|7.030082|10.928576|7.041895|4.766719|448.794386| |7.717921|12.950260|0.259893|7.728111|6.257576|4.402315|3.806793|4.055885|5.383518|22.846762|53.358707| |6.171341|7.563775|0.156994|6.214853|5.120274|4.004336|3.666710|3.993871|5.107924|22.573367|17.849857|36.858105| |5.519536|7.846226|0.220518|5.491247|5.206290|3.834538|3.231707|3.283787|4.040808|20.282167|19.136192|7.731957|36.858105| |5.010323|6.929913|0.239414|5.046664|5.033105|3.734874|3.099078|3.091587|3.727656|19.676515|11.453087|5.313278|15.791861|73.516695| |4.198719|5.197496|0.140429|4.133848|4.042022|3.222651|2.782538|2.802437|3.300442|18.174765|11.216348|6.960562|13.848288|15.121323|53.358707| |3.317276|3.916724|0.111254|3.277651|3.318440|2.760958|2.393703|2.371477|2.703280|16.145648|7.165711|4.643396|7.804947|12.220237|18.824311|36.858105| |2.822210|3.201361|0.088872|2.779432|2.808151|2.420654|2.142062|2.123741|2.375460|14.779433|5.638504|4.001369|5.322408|8.382233|11.309732|14.929838|53.358707| |2.415586|2.697602|0.076484|2.387744|2.442855|2.149445|1.909883|1.878933|2.069093|13.423418|4.476692|3.129270|4.106809|7.016259|7.425075|8.664667|19.000363|53.358707| |2.427741|2.734899|0.079790|2.410602|2.493004|2.182683|1.920400|1.877809|2.068422|13.476172|4.420802|2.955513|4.165011|7.633544|6.978192|8.126639|11.835792|20.453421|36.858105| |2.977978|3.490432|0.105768|2.970420|3.086529|2.600426|2.236015|2.185186|2.456015|15.281330|5.705766|3.520275|5.967627|12.118325|9.344839|10.993095|10.191666|10.193053|10.987559|388.023441| |17.578903|8.880518|0.219529|5.451883|4.111740|3.242028|3.075301|3.513463|4.720294|19.319936|9.644595|5.599846|5.696982|9.367205|5.996343|3.526427|4.059531|3.478259|2.578355|22.625104|0.500000| |17.568473|8.812032|0.214353|6.750860|4.667551|3.743327|3.707987|4.506448|6.485608|22.587081|7.608343|4.659136|4.406112|7.587659|4.707743|2.858157|3.354534|2.940426|2.193760|18.944053|0.301502|0.500000| |17.562370|8.690613|0.173808|6.539892|4.470656|3.612330|3.616914|4.457048|6.487192|22.142601|9.330249|6.683929|4.816122|7.435575|5.362782|3.108734|3.703507|3.151761|2.282991|19.303529|0.301807|0.301505|0.500000| |4.568774|7.121167|0.208232|8.907084|17.711494|8.970758|5.671832|4.962322|5.667935|31.640794|8.903332|4.986447|6.119123|11.110626|6.271939|3.818574|4.270595|3.714760|2.830976|25.817734|0.111390|0.117320|0.112028|0.500000| |3.204921|4.101497|0.112155|5.614899|8.913791|17.746871|8.913624|5.648893|4.960287|53.746818|5.155174|3.466759|3.489198|6.168690|4.111528|2.667044|3.210220|2.892223|2.170333|18.209474|0.078235|0.087325|0.084303|0.215736|0.500000| |3.835106|4.045141|0.098803|5.621587|4.964979|5.645196|8.943219|17.746220|8.886618|53.783367|4.644717|3.457769|2.819195|4.729262|3.356689|2.117522|2.619405|2.335590|1.708302|13.908926|0.087453|0.111640|0.111690|0.107721|0.124287|0.500000| |7.300100|6.802277|0.146925|8.892228|5.654483|4.960227|5.686131|8.987118|17.741026|31.695633|6.819097|4.941950|3.758859|6.124746|4.253612|2.568575|3.102706|2.705462|1.977030|16.517889|0.143800|0.213361|0.227024|0.124112|0.107688|0.216833|0.500000| |4.644644|5.790134|0.131006|5.374001|4.958981|4.037394|3.626115|3.765802|4.487655|22.824103|12.312136|17.576027|6.921598|8.704318|9.698143|4.857819|5.864452|4.512974|3.070933|25.389407|0.119244|0.104507|0.136040|0.137712|0.099829|0.090831|0.116260|0.500000| |5.702302|5.978255|0.132703|4.776430|4.002206|3.269138|3.068186|3.363618|4.185003|19.642156|12.244435|17.540175|6.621261|8.417612|9.091165|4.611023|5.608949|4.347666|2.959299|24.357773|0.156270|0.120177|0.178474|0.109782|0.080435|0.083793|0.118438|0.298950|0.500000| |6.584802|7.520508|0.148666|7.082240|5.362706|4.312742|4.159854|4.801723|6.408084|24.985448|12.536800|17.667671|5.733572|7.833075|6.845229|3.692755|4.446611|3.622331|2.540874|21.171978|0.151723|0.140849|0.220011|0.133898|0.100325|0.115223|0.176705|0.304628|0.302178|0.500000| |4.044236|4.784362|0.122416|3.938978|3.771686|3.086904|2.730111|2.782137|3.258919|17.971919|10.289327|8.028720|9.152159|10.790544|26.078057|9.577709|10.793363|6.915357|4.468959|37.405371|0.116279|0.092017|0.110617|0.114309|0.079949|0.068698|0.086850|0.244166|0.231414|0.153683|0.500000| |2.170152|2.412894|0.070760|2.158733|2.240877|1.993000|1.764902|1.720485|1.875674|12.547041|3.778184|2.539868|3.435879|6.425752|5.439738|5.596756|8.080363|12.612957|17.777576|54.689380|0.063849|0.055290|0.056739|0.070154|0.055466|0.043751|0.049903|0.072904|0.070566|0.061920|0.099202|0.500000|
1610.282981 -7010.124309 2338.931931 -154.431417 -3215.340814 1603.714926 -1611.625888 2.000834 403800000000002F 42F89FEA136A9FFE 4284779DFC30BA2D 411489FFFFFFFFFF B7C16C2614EA0800 4276C425BD4C0000